TNFSF9 Produits
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
Catégories
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008].
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Catégories TNFSF9 en vedette
TNFSF9 Anticorps
High quality antibodies with extensive validation data.
TNFSF9 Kits ELISA
Reliable ELISA kits for a wide range of species.
TNFSF9 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TNFSF9 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, ICC, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (3)
- (1)
N° du produit
ABIN705056
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7441109
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7443173
Quantité
100 μL
Fiche technique
Fiche technique
TNFSF9 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970952
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960265
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN4881698
Quantité
96 tests
Fiche technique
Fiche technique
TNFSF9 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7273929
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7273928
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7273927
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TNFSF9
: "Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis." dans: Circulation research, Vol. 122, Issue 12, pp. 1661-1674, (2019) (PubMed).: "Crystal structure of the human 4-1BB/4-1BBL complex." dans: The Journal of biological chemistry, Vol. 293, Issue 25, pp. 9880-9891, (2018) (PubMed).
: "The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily." dans: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9202-10, (2010) (PubMed).
: "Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling." dans: PLoS ONE, Vol. 5, Issue 5, pp. e10845, (2010) (PubMed).
: "Mantle cell lymphomas acquire increased expression of CCL4, CCL5 and 4-1BB-L implicated in cell survival." dans: International journal of cancer, Vol. 118, Issue 8, pp. 2092-7, (2006) (PubMed).
: "Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity." dans: The Journal of biological chemistry, Vol. 280, Issue 50, pp. 41472-81, (2005) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "[Binding between alpha 1A-adrenergic receptor and segment of bone morphogenetic protein-1 in human embryonic cell 293]." dans: Sheng li xue bao : [Acta physiologica Sinica], Vol. 55, Issue 6, pp. 692-8, (2003) (PubMed).
: "Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis." dans: The Journal of experimental medicine, Vol. 191, Issue 2, pp. 375-80, (2000) (PubMed).
: "Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway." dans: European journal of immunology, Vol. 28, Issue 3, pp. 1116-21, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à TNFSF9
TNF superfamily member 9 (Tnfsf9), TNF superfamily member 9 (LOC476729), TNF superfamily member 9 (TNFSF9), tumor necrosis factor (ligand) superfamily, member 9 (Tnfsf9), 4-1BB-L, 4-1BBL, AI848817, Cd137l, CD137L, Ly63l, TNFSF9Protein level used designations for TNFSF9
- costimulatory molecule
- tumor necrosis factor (ligand) superfamily, member 9
- 4-1BB ligand
- tumor necrosis factor ligand superfamily member 9
- 4-1BBL
- homolog of mouse 4-1BB-L
- receptor 4-1BB ligand
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