TRAIL Protéines
(Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
| Catalog no. | Produit | Reactivité | Hôte / Clonalité | Application | Prix et délai de livraison |
|---|---|---|---|---|---|
| TRAIL Protein (AA 118-281, Trimer) (His-DYKDDDDK Tag) | Humain | HEK-293 Cells |
|
215,33 €
Voir le prix
|
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| TRAIL Protein (AA 1-281) (GST tag) | Humain | Wheat germ |
|
624,00 €
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|
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| TRAIL Protein (AA 114-281) (His-DYKDDDDK-Strep II Tag) | Humain | HEK-293T Cells |
|
952,00 €
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|
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| TRAIL Protein (AA 118-291) (His tag) | Souris | Escherichia coli (E. coli) |
|
268,42 €
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|
|
| TRAIL Protein (AA 95-281) (His-IF2DI Tag) | Humain | Escherichia coli (E. coli) |
|
476,92 €
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|
| TRAIL Protein (AA 114-281) | Humain | Escherichia coli (E. coli) |
|
734,62 €
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|
|
| TRAIL Protein (AA 114-281) (mFc Tag) | Humain | Mammalian Cells |
|
378,40 €
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|
|
| TRAIL Protein (AA 115-281) | Humain | Escherichia coli (E. coli) |
|
270,43 €
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|
|
| TRAIL Protein (AA 1-281) (Strep Tag) | Humain | Cell-free protein synthesis (CFPS) |
|
à partir de 15.754,29 €
Voir le prix
|
|
| TRAIL Protein (AA 1-291) (Strep Tag) | Souris | Cell-free protein synthesis (CFPS) |
|
à partir de 15.754,29 €
Voir le prix
|
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| TRAIL Protein (AA 95-281, Extracellular Domain, N-Term, Soluble) (DYKDDDDK Tag) | Humain, Souris | Escherichia coli (E. coli) |
|
163,65 €
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|
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| TRAIL Protein (AA 114-281) | Humain | Escherichia coli (E. coli) |
|
251,79 €
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|
|
| TRAIL Protein (AA 1-281) | Humain | Escherichia coli (E. coli) |
|
117,19 €
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|
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| TRAIL Protein (AA 1-291) | Souris | Escherichia coli (E. coli) |
|
117,19 €
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|
|
| TRAIL Protein (His tag) | Souris | Escherichia coli (E. coli) |
|
278,46 €
Voir le prix
|
|
| TRAIL Protein (His tag) | Humain | Escherichia coli (E. coli) |
|
278,46 €
Voir le prix
|
|
| TRAIL Protein (AA 118-291) (TRX tag) | Souris | Escherichia coli (E. coli) |
|
1.778,00 €
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|
|
| TRAIL Protein (AA 118-291) (GST tag) | Souris | Escherichia coli (E. coli) |
|
1.778,00 €
Voir le prix
|
|
| TRAIL Protéine | Humain | Wheat germ |
|
918,40 €
Voir le prix
|
|
| TRAIL Protein (His tag) | Souris | Escherichia coli (E. coli) |
|
287,60 €
Voir le prix
|
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- ELISA (ELISA: Image de validation disponible)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Image de validation disponible)
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Protein
- AP (Affinity Purification: Application indiquée)
- AA (Antibody Array: Application indiquée)
- ELISA (ELISA: Application indiquée)
- WB (Western Blotting: Application indiquée)
1 reference - Origine
- Humain
- Hôte
- Wheat germ
- Type Proteine
- Recombinant
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- WB (Western Blotting: Image de validation disponible)
- ELISA (ELISA: Application indiquée)
- PI (Protein Interaction: Application indiquée)
- Origine
- Humain
- Hôte
- HEK-293T Cells
- Type Proteine
- Recombinant
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Tris-Bis PAGE
Protein
- WB (Western Blotting: Image de validation disponible)
- ELISA (ELISA: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 95 %
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- Origine
- Humain
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- Greater than 95 % as determined by SDS-PAGE.
Protein
- Func (Functional Studies: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Activité biologique
- Active
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Classe de qualité
- custom-made
- Origine
- Humain
- Hôte
- Cell-free protein synthesis (CFPS)
- Type Proteine
- Recombinant
- Pureté
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Classe de qualité
- custom-made
- Origine
- Souris
- Hôte
- Cell-free protein synthesis (CFPS)
- Type Proteine
- Recombinant
- Pureté
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: Application indiquée)
- Origine
- Humain, Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- >95 % (SDS-PAGE)
- Activité biologique
- Active
Protein
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Activité biologique
- Active
Protein
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- >95 % , as determined by SDS-PAGE and HPLC
- Activité biologique
- Active
Protein
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- >95 % , as determined by SDS-PAGE and HPLC
- Activité biologique
- Active
Protein
- WB (Western Blotting: Application indiquée)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- >98 %
- Activité biologique
- Active
Protein
- WB (Western Blotting: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- >98 %
- Activité biologique
- Active
Protein
- Imm (Immunogen: Application indiquée)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: Application indiquée)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
Protein
- AP (Affinity Purification: Application indiquée)
- Func (Functional Studies: Application indiquée)
- ScA (Screening Assay: Application indiquée)
- Origine
- Humain
- Hôte
- Wheat germ
- Type Proteine
- Recombinant
Protein
- CC (Cell Culture: Application indiquée)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 98 % as determined by reducing SDS-PAGE.
- Activité biologique
- Active
Dernières publications pour nos TRAIL Protéines
: "Up-regulation of miR-146b and down-regulation of miR-200b contribute to the cytotoxic effect of histone deacetylase inhibitors on ras-transformed thyroid cells." dans: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 6, pp. E1031-40, (2013) (PubMed).
: "Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family." dans: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12687-90, (1996) (PubMed).
: "Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family." dans: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12687-90, (1996) (PubMed).
Pseudonymes pour TRAIL Protéines
TNF superfamily member 10 (TNFSF10) Protéinestumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10) Protéines
TNF superfamily member 10 (Tnfsf10) Protéines
tumor necrosis factor superfamily member 10 (TNFSF10) Protéines
TNF superfamily member 10 S homeolog (tnfsf10.S) Protéines
TNF superfamily member 10 (tnfsf10) Protéines
A330042I21Rik Protéines
AI448571 Protéines
Apo-2L Protéines
APO-2L Protéines
apo-2l Protéines
APO2L Protéines
apo2l Protéines
CD253 Protéines
cd253 Protéines
Ly81 Protéines
TL2 Protéines
tl2 Protéines
tnfsf10l2 Protéines
TNLG6A Protéines
TRAIL Protéines
Trail Protéines
trail Protéines
trail1 Protéines
xtrail1 Protéines
zgc:92320 Protéines
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