TXNRD1 Produits
(Thioredoxin Reductase 1 (TXNRD1))
Catégories
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008].
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Catégories TXNRD1 en vedette
TXNRD1 Anticorps
High quality antibodies with extensive validation data.
TXNRD1 Kits ELISA
Reliable ELISA kits for a wide range of species.
TXNRD1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TXNRD1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7432433
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (4)
N° du produit
ABIN1386102
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, ICC, IHC (p)
Validations
- (5)
N° du produit
ABIN2855577
Quantité
100 μL
Fiche technique
Fiche technique
TXNRD1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962389
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6973702
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959909
Quantité
96 tests
Fiche technique
Fiche technique
TXNRD1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324248
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125363
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7391732
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TXNRD1
: "Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism." dans: Free radical biology & medicine, Vol. 127, pp. 182-189, (2018) (PubMed).: "Monitoring thioredoxin redox with a genetically encoded red fluorescent biosensor." dans: Nature chemical biology, Vol. 13, Issue 9, pp. 1045-1052, (2017) (PubMed).
: "Intratumoral hemorrhage-related differences in the expression of vascular endothelial growth factor, basic fibroblast growth factor and thioredoxin reductase 1 in human glioblastoma." dans: Molecular and clinical oncology, Vol. 5, Issue 4, pp. 343-346, (2016) (PubMed).
: "The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition." dans: PLoS ONE, Vol. 11, Issue 1, pp. e0147773, (2016) (PubMed).
: "Thioredoxin reductase as a novel molecular target for cancer therapy." dans: Cancer letters, Vol. 236, Issue 2, pp. 164-74, (2006) (PubMed).
: "On the potential of thioredoxin reductase inhibitors for cancer therapy." dans: Seminars in cancer biology, Vol. 16, Issue 6, pp. 452-65, (2006) (PubMed).
: "Thioredoxin reductase." dans: The Biochemical journal, Vol. 346 Pt 1, pp. 1-8, (2000) (PubMed).
: "Cloning and sequencing of a human thioredoxin reductase." dans: FEBS letters, Vol. 373, Issue 1, pp. 5-9, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à TXNRD1
thioredoxin reductase 1 (TXNRD1), thioredoxin reductase 1 (txnrd1), thioredoxin reductase 1 (Trxr-1), thioredoxin reductase 1 L homeolog (txnrd1.L), NADPH-dependent thioredoxin reductase C (NTRC), ThioRedoXin Reductase (trxr-1), thioredoxin reductase 1 (Txnrd1), cb682, fb83a08, GB14972, GRIM-12, MGC85342, NADPH-dependent thioredoxin reductase C, T32G6.20, T32G6_20, TR, Tr, TR1, TrxR1, TRXR1, TXNR, wu:fb83a08Protein level used designations for TXNRD1
- thioredoxin reductase 1, cytoplasmic
- thioredoxin reductase 3
- thioredoxin reductase 1
- thioredoxin reductase 1, cytoplasmic-like
- KM-102-derived reductase-like factor
- gene associated with retinoic and IFN-induced mortality 12 protein
- gene associated with retinoic and interferon-induced mortality 12 protein
- oxidoreductase
- thioredoxin reductase GRIM-12
- thioredoxin reductase TR1
- TR
- redox enzyme thioredoxin reductase
- NADPH-dependent thioredoxin reductase
- selenoprotein oxidoreductase
- TR alpha
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