UBA3 Produits
(Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
Catégories
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories UBA3 en vedette
UBA3 Anticorps
High quality antibodies with extensive validation data.
UBA3 Kits ELISA
Reliable ELISA kits for a wide range of species.
UBA3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
UBA3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
N° du produit
ABIN387909
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (2)
N° du produit
ABIN6265835
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN3043952
Quantité
100 μg
Fiche technique
Fiche technique
UBA3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971051
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1144447
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1144448
Quantité
96 tests
Fiche technique
Fiche technique
UBA3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324294
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125641
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3074969
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits UBA3
: "The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis." dans: Nature communications, Vol. 5, pp. 3733, (2014) (PubMed).: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8." dans: Nature, Vol. 422, Issue 6929, pp. 330-4, (2003) (PubMed).
: "Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer." dans: The Journal of biological chemistry, Vol. 278, Issue 29, pp. 26823-30, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à UBA3
ubiquitin like modifier activating enzyme 3 (UBA3), ubiquitin-like modifier activating enzyme 3 (Uba3), ubiquitin-like modifier activating enzyme 3 (uba3), ubiquitin like modifier activating enzyme 3 (uba3), ubiquitin like modifier activating enzyme 3 S homeolog (uba3.S), A830034N06Rik, AI256736, AI848246, AW546539, hUBA3, UBE1C, Ube1c, ube1c, wu:fb75e04, wu:fc37b11, zgc:55528Protein level used designations for UBA3
- NEDD8-activating enzyme E1 catalytic subunit
- NEDD8-activating enzyme E1C
- Nedd8-activating enzyme hUba3
- UBA3, ubiquitin-activating enzyme E1 homolog
- ubiquitin-activating enzyme 3
- ubiquitin-activating enzyme E1C (UBA3 homolog, yeast)
- ubiquitin-activating enzyme E1C (homologous to yeast UBA3)
- ubiquitin-like modifier-activating enzyme 3
- ubiquitin activating enzyme 3
- ubiquitin-activating enzyme E1C
- ubiquitin-like modifier activating enzyme 3
- NEDD8-activating enzyme E1 catalytic subunit-like
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