Utrophin Produits
(Utrophin (UTRN))
Catégories
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described\; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008].
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Catégories Utrophin en vedette
Utrophin Anticorps
High quality antibodies with extensive validation data.
Utrophin Kits ELISA
Reliable ELISA kits for a wide range of species.
Utrophin Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Utrophin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7443953
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
N° du produit
ABIN563360
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IF
Validations
- (5)
- (3)
N° du produit
ABIN968237
Quantité
50 μg
Fiche technique
Fiche technique
Utrophin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971089
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960406
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960407
Quantité
96 tests
Fiche technique
Fiche technique
Utrophin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324869
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7417648
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7408324
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Utrophin
: "Muscle and neural isoforms of agrin increase utrophin expression in cultured myotubes via a transcriptional regulatory mechanism." dans: The Journal of biological chemistry, Vol. 273, Issue 2, pp. 736-43, (1998) (PubMed).: "Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy." dans: Cell, Vol. 90, Issue 4, pp. 717-27, (1997) (PubMed).
: "Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy." dans: Cell, Vol. 90, Issue 4, pp. 729-38, (1997) (PubMed).
: "Cloning and expression of full length mouse utrophin: the differential association of utrophin and dystrophin with AChR clusters." dans: FEBS letters, Vol. 398, Issue 2-3, pp. 259-64, (1997) (PubMed).
: "Primary structure of dystrophin-related protein." dans: Nature, Vol. 360, Issue 6404, pp. 591-3, (1993) (PubMed).
Synonymes et noms alternatifs relatifs à Utrophin
utrophin L homeolog (utrn.L), utrophin (UTRN), utrophin (LOAG_03796), utrophin (utrn), utrophin (LOC100551145), utrophin (Utrn), AA589569, DKFZp469A0710, dmdl, DMDL, Dmdl, drp, DRP, drp1, DRP1Protein level used designations for Utrophin
- utrophin
- utrophin, or dystrophin-related protein 1
- DRP-1
- dystrophin-related protein 1
- utrophin (homologous to dystrophin)
- G-utrophin
- urotrophin
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