UVRAG Produits
(UV Radiation Resistance Associated Gene (UVRAG))
Catégories
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008].
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Catégories UVRAG en vedette
UVRAG Anticorps
High quality antibodies with extensive validation data.
UVRAG Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
UVRAG recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
- (4)
N° du produit
ABIN6150044
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (4)
N° du produit
ABIN7175178
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (7)
- (3)
N° du produit
ABIN388586
Quantité
400 μL
Fiche technique
Fiche technique
UVRAG recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6201850
Quantité
96 tests
Fiche technique
Fiche technique
UVRAG recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324875
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324874
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3096275
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits UVRAG
: "NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex." dans: Frontiers in cellular and infection microbiology, Vol. 8, pp. 403, (2019) (PubMed).: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." dans: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).
: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." dans: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).
: "Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells." dans: Neural regeneration research, Vol. 9, Issue 1, pp. 16-24, (2014) (PubMed).
: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
: "The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression." dans: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 185-91, (2011) (PubMed).
: "RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly." dans: Cell, Vol. 144, Issue 2, pp. 253-67, (2011) (PubMed).
: "Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a ?-secretase-independent manner." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 8, pp. 2781-91, (2011) (PubMed).
: "Rubicon controls endosome maturation as a Rab7 effector." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 45, pp. 19338-43, (2010) (PubMed).
: "Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment." dans: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1371-83, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à UVRAG
UV radiation resistance associated (UVRAG), UV radiation resistance associated gene (Uvrag), UV radiation resistance associated gene (uvrag), UV radiation resistance associated (Uvrag), UV radiation resistance associated S homeolog (uvrag.S), UV radiation resistance associated L homeolog (uvrag.L), UV radiation resistance associated (uvrag), UV-resistance associated gene (Uvrag), 9530039D02Rik, AI648770, BB124205, CG6116, DHTX, Dmel\\CG6116, MGC81810, MGC131135, p63, uvrag, UVRAG, Uvrag1, Uvragl, VPS38, zgc:56164Protein level used designations for UVRAG
- UV radiation resistance-associated gene protein
- beclin 1 binding protein
- disrupted in heterotaxy
- UV radiation resistance associated
- UV radiation resistance associated gene
- UV radiation resistance-associated gene protein-like
- CG6116-PA
- CG6116-PB
- Uvrag-PA
- Uvrag-PB
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