Vascular Endothelial Growth Factor A Protéines
(Vascular Endothelial Growth Factor A (VEGFA))
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008].
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VEGFA
Origine: Chien
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
VEGFA
Origine: Poulet
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
VEGFA
Origine: Rat
Hôte: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
VEGFA
Origine: Souris
Hôte: Cellules d'insectes
Recombinant
> 90 % by SDS-PAGE
Active
VEGFA
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS-PAGE
Active
VEGFA
Origine: Rat
Hôte: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
VEGFA
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
VEGFA
Origine: Souris
Hôte: Insect cells (Sf9)
Recombinant
>95 % (SDS-PAGE)
SDS
Active
VEGFA
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS-PAGE
Active
VEGFA
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS-PAGE
Active
VEGFA
Origine: Souris
Hôte: Cellules d'insectes
Recombinant
> 90 % by SDS-PAGE
Active
VEGFA
Origine: Souris
Hôte: Escherichia coli (E. coli)
> 96 % by SDS-PAGE and HPLC analyses.
Active
VEGFA
Origine: Souris
Hôte: Levure
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
VEGFA
Origine: Rat
Hôte: Mammalian Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
VEGFA
Origine: Boeuf (Vache)
Hôte: HEK-293 Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
VEGFA
Origine: Porc
Hôte: HEK-293 Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
VEGFA
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
VEGFA
Origine: Rat
Hôte: Levure
Recombinant
Greater than 95 % as determined by SDS-PAGE.
WB, ELISA
VEGFA
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CC
Active
VEGFA
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
ELISA
Active
Dernières publications pour nos Vascular Endothelial Growth Factor A Protéines
: "Fisetin inhibits vascular endothelial growth factor-induced angiogenesis in retinoblastoma cells." dans: Oncology letters, Vol. 20, Issue 2, pp. 1239-1244, (2020) (PubMed).
: "Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition." dans: Cell research, Vol. 29, Issue 11, pp. 895-910, (2020) (PubMed).
: "An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells." dans: Scientific reports, Vol. 9, Issue 1, pp. 16954, (2019) (PubMed).
: "PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs." dans: Nature communications, Vol. 8, Issue 1, pp. 672, (2018) (PubMed).
: "Directing and Potentiating Stem Cell-Mediated Angiogenesis and Tissue Repair by Cell Surface E-Selectin Coating." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0154053, (2017) (PubMed).
: "Efficient Production of a Bioactive Bevacizumab Monoclonal Antibody Using the 2A Self-cleavage Peptide in Transgenic Rice Callus." dans: Frontiers in plant science, Vol. 7, pp. 1156, (2016) (PubMed).
: "The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing." dans: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 11947-54, (1991) (PubMed).
: "Vascular endothelial growth factor is a secreted angiogenic mitogen." dans: Science (New York, N.Y.), Vol. 246, Issue 4935, pp. 1306-9, (1990) (PubMed).
: "Vascular permeability factor, an endothelial cell mitogen related to PDGF." dans: Science (New York, N.Y.), Vol. 246, Issue 4935, pp. 1309-12, (1990) (PubMed).
: "Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition." dans: Cell research, Vol. 29, Issue 11, pp. 895-910, (2020) (PubMed).
: "An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells." dans: Scientific reports, Vol. 9, Issue 1, pp. 16954, (2019) (PubMed).
: "PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs." dans: Nature communications, Vol. 8, Issue 1, pp. 672, (2018) (PubMed).
: "Directing and Potentiating Stem Cell-Mediated Angiogenesis and Tissue Repair by Cell Surface E-Selectin Coating." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0154053, (2017) (PubMed).
: "Efficient Production of a Bioactive Bevacizumab Monoclonal Antibody Using the 2A Self-cleavage Peptide in Transgenic Rice Callus." dans: Frontiers in plant science, Vol. 7, pp. 1156, (2016) (PubMed).
: "The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing." dans: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 11947-54, (1991) (PubMed).
: "Vascular endothelial growth factor is a secreted angiogenic mitogen." dans: Science (New York, N.Y.), Vol. 246, Issue 4935, pp. 1306-9, (1990) (PubMed).
: "Vascular permeability factor, an endothelial cell mitogen related to PDGF." dans: Science (New York, N.Y.), Vol. 246, Issue 4935, pp. 1309-12, (1990) (PubMed).
Pseudonymes pour Vascular Endothelial Growth Factor A Protéines
vascular endothelial growth factor A (VEGFA) Protéinesvascular endothelial growth factor A (Vegfa) Protéines
vascular endothelial growth factor Aa (vegfaa) Protéines
vascular endothelial growth factor A L homeolog (vegfa.L) Protéines
vascular endothelial growth factor A (vegfa) Protéines
vascular endothelial growth factor Ab (vegfab) Protéines
eVEGF120 Protéines
eVEGF164 Protéines
MVCD1 Protéines
si:dkey-14d8.3 Protéines
vefg Protéines
VEGF Protéines
Vegf Protéines
vegf Protéines
VEGF-A Protéines
vegf-a Protéines
Vegf120 Protéines
Vegf164 Protéines
VEGF164 Protéines
Vegf188 Protéines
vegfa Protéines
VPF Protéines
Vpf Protéines
vpf Protéines
wu:fd42e02 Protéines
wu:fj82c06 Protéines
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