WWP1 Proteins

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1\; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.

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WWP1 Protein (AA 1-922) (His tag)

custom-made WWP1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant WWP1 Protein, UniprotID Q9H0M0

3 images

N° du produit ABIN7556022

Détails

WWP1 Protein (AA 1-233) (His-IF2DI Tag)

WWP1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

Western Blotting (WB) image for WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) (AA 1-233) protein (His-IF2DI Tag) (ABIN7125747)

1 image

N° du produit ABIN7125747

Détails

WWP1 Protein (AA 1-922) (Strep Tag)

custom-made WWP1 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3096355

Détails

WWP1 Protéines

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Pseudonymes pour WWP1 Protéines

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