XAF1 Produits
(XiAP Associated Factor 1 (XAF1))
Catégories
This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
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Catégories XAF1 en vedette
XAF1 Anticorps
High quality antibodies with extensive validation data.
XAF1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
XAF1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
N° du produit
ABIN674754
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
N° du produit
ABIN527175
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (2)
- (2)
N° du produit
ABIN540591
Quantité
100 μg
Fiche technique
Fiche technique
XAF1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971212
Quantité
96 tests
Fiche technique
Fiche technique
XAF1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125752
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325416
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325418
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits XAF1
: "SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease." dans: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 743-756, (2019) (PubMed).: "Admixture fine-mapping in African Americans implicates XAF1 as a possible sarcoidosis risk gene." dans: PLoS ONE, Vol. 9, Issue 3, pp. e92646, (2014) (PubMed).
: "A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer." dans: Nature genetics, Vol. 45, Issue 7, pp. 747-55, (2013) (PubMed).
: "Combination of DNA methylation inhibitor 5-azacytidine and arsenic trioxide has synergistic activity in myeloma." dans: European journal of haematology, Vol. 82, Issue 3, pp. 176-83, (2009) (PubMed).
: "Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer." dans: BMC cancer, Vol. 9, pp. 276, (2009) (PubMed).
: "Wild-type PABPN1 is anti-apoptotic and reduces toxicity of the oculopharyngeal muscular dystrophy mutation." dans: Human molecular genetics, Vol. 17, Issue 8, pp. 1097-108, (2008) (PubMed).
: "XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway." dans: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 13059-72, (2007) (PubMed).
: "Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP." dans: Molecular and cellular biochemistry, Vol. 286, Issue 1-2, pp. 67-76, (2006) (PubMed).
: "The Bcl-2 protein family and its role in the development of neoplastic disease." dans: Experimental gerontology, Vol. 39, Issue 8, pp. 1125-35, (2004) (PubMed).
: "X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia." dans: Neurobiology of disease, Vol. 16, Issue 1, pp. 179-89, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à XAF1
XIAP associated factor 1 (xaf1), XIAP associated factor 1 (XAF1), XIAP associated factor 1 (Xaf1), BIRC4BP, Fbxo39, HSXIAPAF1, XIAPAF1Protein level used designations for XAF1
- XIAP-associated factor 1
- BIRC4 binding protein
- BIRC4-binding protein
- F-box protein 39
- novel TRAF-type zinc finger protein
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