XIAP Produits
(X-Linked Inhibitor of Apoptosis (XIAP))
Catégories
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011].
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Catégories XIAP en vedette
XIAP Anticorps
High quality antibodies with extensive validation data.
XIAP Kits ELISA
Reliable ELISA kits for a wide range of species.
XIAP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
XIAP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (5)
N° du produit
ABIN2854771
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
N° du produit
ABIN6256441
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (4)
- (3)
N° du produit
ABIN674364
Quantité
100 μL
Fiche technique
Fiche technique
XIAP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6960570
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971208
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN625470
Quantité
96 tests
Fiche technique
Fiche technique
XIAP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125749
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505227
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7417597
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits XIAP
: "Distinctive expression signatures of serum microRNAs in ischaemic stroke and transient ischaemic attack patients." dans: Thrombosis and haemostasis, Vol. 117, Issue 5, pp. 992-1001, (2018) (PubMed).: "Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling." dans: Journal of cell science, Vol. 131, Issue 10, (2018) (PubMed).
: "Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke." dans: Journal of biophotonics, (2017) (PubMed).
: "Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice." dans: Marine drugs, Vol. 15, Issue 3, (2017) (PubMed).
: "Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis." dans: Oncotarget, Vol. 7, Issue 8, pp. 9477-90, (2017) (PubMed).
: "Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer." dans: Journal of bioenergetics and biomembranes, (2015) (PubMed).
: "Gene transfection mediated by polyethyleneimine-polyethylene glycol nanocarrier prevents cisplatin-induced spiral ganglion cell damage." dans: Neural regeneration research, Vol. 10, Issue 3, pp. 425-31, (2015) (PubMed).
: "Smac mimetic?induced caspase?independent necroptosis requires RIP1 in breast cancer." dans: Molecular medicine reports, (2015) (PubMed).
: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." dans: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, (2014) (PubMed).
: "Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549." dans: PLoS ONE, Vol. 8, Issue 11, pp. e79201, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à XIAP
X-linked inhibitor of apoptosis (XIAP), X-linked inhibitor of apoptosis (xiap), X-linked inhibitor of apoptosis L homeolog (xiap.L), X-linked inhibitor of apoptosis (Xiap), 1110015C02Rik, Aipa, API3, api3, Api3, BIRC4, birc4, Birc4, BIRC8, fb73d01, hIAP-3, hIAP3, IAP-3, IAP3, ILP-1, ILP1, ilp1, MIHA, miha, mXIAP, riap3, wu:fb73d01, XLP2, xlp2, xxiap, zgc:91873Protein level used designations for XIAP
- E3 ubiquitin-protein ligase XIAP
- IAP-like protein
- X-linked IAP
- baculoviral IAP repeat-containing protein 4
- inhibitor of apoptosis protein 3
- Baculoviral IAP repeat-containing protein 4
- X-linked inhibitor of apoptosis protein
- baculoviral IAP repeat-containing 4
- baculoviral IAP-repeat containing protein 4
- IAP homolog A
- IAP-3
- apoptosis inhibitor 3
- mIAP-3
- mIAP3
- RIAP-3
- apoptosis inhibitor protein 3
- baculoviral IAP repeat containing 8
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