CD28 anticorps
Aperçu rapide pour CD28 anticorps (ABIN135188)
Antigène
Voir toutes CD28 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Hamster Anti-Mouse CD28-LE/AF
-
Specificité
- Mouse CD28, Mr 40 kDa
-
Attributs du produit
- Low Endotoxin/Azide Free Anti-Mouse CD28 antibody for use in flow cytometry, immunoprecipitation, costimulation, and stimulation assays.
-
niveau d'endotoxine
- Low Endotoxin
-
Immunogène
- C57BL/6N mouse T cell lymphoma EL4 cell line
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Phosphate buffered saline, pH 7.4
-
Agent conservateur
- Azide free
-
Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
-
Stock
- 4 °C
-
Stockage commentaire
- 2-8°C
-
-
- CD28
-
Autre désignation
- CD28
-
Sujet
- CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
-
ID gène
- 12487
-
UniProt
- P31041
-
Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Antigène
-