PDGFRA anticorps (PE)
Aperçu rapide pour PDGFRA anticorps (PE) (ABIN457360)
Antigène
Voir toutes PDGFRA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Anti-Hu CD140a PE
-
Réactivité croisée (Details)
- Human
-
Attributs du produit
- The mouse monoclonal antibody 16A1 recognizes an extracellular epitope of CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
-
Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
-
Immunogène
- CD140a-transfected NIH 3T3 cells
-
Isotype
- IgG1, kappa
-
-
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibody
PDGFRA Reactivité: Humain ELISA, IHC, FACS Hôte: Souris Monoclonal 5B11G5 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 698-727) antibodyPDGFRA Reactivité: Souris WB, IHC (p) Hôte: Lapin Polyclonal RB11101 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 361-528) antibodyPDGFRA Reactivité: Humain ELISA, FACS, ICC Hôte: Souris Monoclonal 8E12F2 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1048-1077), (C-Term) antibodyPDGFRA Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB2005-2006 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 331-719) antibodyPDGFRA Reactivité: Humain WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibodyPDGFRA Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 1A10A8 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1048-1077) antibodyPDGFRA Reactivité: Humain, Souris WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 25-218) antibodyPDGFRA Reactivité: Humain WB, ELISA, PLA Hôte: Souris Monoclonal 4H1-1C9 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-1089) antibodyPDGFRA Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1035-1053) antibodyPDGFRA Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet, Singe, Porc, Lapin, Cheval, Xenopus laevis, Roussette (Chauve-souris), Hamster WB, IHC, IHC (p), IP Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Do not freeze,Protect from prolonged exposure to light
-
Stock
- 4 °C
-
Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
-
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
-
Autre désignation
- CD140a
-
Sujet
- Platelet derived growth factor receptor alpha,CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.,PDGFRA, PDGFR2
-
ID gène
- 5156
-
UniProt
- P16234
-
Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
Antigène
-
