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ACVR2B anticorps (AA 1-30)

Cet anticorps Lapin Polyclonal détecte spécifiquement ACVR2B dans WB. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Western blot analysis of lysate from human pancreas tissue lysate, using ACVR2B Antibody (S14) A. (ACVR2B anticorps (AA 1-30))

2 images

(1 reference)

N° du produit ABIN391162

434,77 €

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Destination: France

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Aperçu rapide pour ACVR2B anticorps (AA 1-30) (ABIN391162)

Antigène

Voir toutes ACVR2B Anticorps

ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Reactivité

Humain

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp ACVR2B est non-conjugé

Application

Western Blotting (WB)

Clone

RB08166

Discover our top product ACVR2B Anticorps primaire

Épitope
15

8

7

7

6

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 1-30

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène

This ACVR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected between aa 1 and 30 of human ACVR2B.

Isotype

Ig Fraction
anti-Activin A Receptor, Type IIB (ACVR2B) (Middle Region) antibody
ACVR2B Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor, Type IIB (ACVR2B) (AA 45-150) antibody
ACVR2B Reactivité: Humain, Rat WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor, Type IIB (ACVR2B) (AA 148-176) antibody
ACVR2B Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB34444 unconjugated

anti-Activin A Receptor, Type IIB (ACVR2B) (AA 21-120) antibody
ACVR2B Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1C11 unconjugated

anti-Activin A Receptor, Type IIB (ACVR2B) antibody
ACVR2B Reactivité: Humain IHC, ELISA Hôte: Lapin Monoclonal 7B10 unconjugated Recombinant Antibody

anti-Activin A Receptor, Type IIB (ACVR2B) (Extracellular Domain) antibody
ACVR2B Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor, Type IIB (ACVR2B) (AA 50-150) antibody
ACVR2B Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor, Type IIB (ACVR2B) (Internal Region) antibody
ACVR2B Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated

anti-Activin A Receptor, Type IIB (ACVR2B) (AA 21-120) antibody
ACVR2B Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated

anti-Activin A Receptor, Type IIB (ACVR2B) (AA 214-350) antibody
ACVR2B Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB: 1:1000. WB: 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
McKay, Ogborn, Bellamy, Tarnopolsky, Parise: "Myostatin is associated with age-related human muscle stem cell dysfunction." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 6, pp. 2509-21, (2012) (PubMed).
Antigène

ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Autre désignation

ACVR2B

Sujet

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B (activin A type IIB receptor) displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

Poids moléculaire

57724

ID gène

93

NCBI Accession

NP_001097

UniProt

Q13705

Pathways

Hormone Transport, Cancer Immune Checkpoints