ACVR2B anticorps (AA 50-150)

N° du produit ABIN7265414

Détail du produit anti-ACVR2B anticorps

Antigène: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Épitope: AA 50-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVR2B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: ACVR2B Rabbit pAb

Séquence: EGEQDKRLHC YASWRNSSGT IELVKKGCWL DDFNCYDRQE CVATEENPQV YFCCCEGNFC NERFTHLPEA GGPEVTYEPP PTAPTLLTVL AYSLLPIGGL S

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACVR2B (NP_001097.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ACVR2B

Antigène: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Autre désignation: ACVR2B (ACVR2B Produits)

Synonymes: anticorps ACVR2B, anticorps XAR1, anticorps actr-iib, anticorps actriib, anticorps ACTRIIB, anticorps ActR-IIB, anticorps HTX4, anticorps ActRIIB, anticorps actr2b, anticorps actrIIb, anticorps wu:fj97d11, anticorps activin A receptor type 2B, anticorps activin A receptor type 2B L homeolog, anticorps activin A receptor type 2Ba, anticorps activin receptor IIB, anticorps ACVR2B, anticorps acvr2b, anticorps acvr2b.L, anticorps Acvr2b, anticorps acvr2ba

Sujet: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.,ACVR2B,ACTRIIB,ActR-IIB,HTX4,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Stem Cells,ACVR2B

Poids moléculaire: 57kDa

ID gène: 93

UniProt: Q13705

Pathways: Hormone Transport, Cancer Immune Checkpoints