ACVR2B anticorps (Extracellular Domain)

N° du produit ABIN2745505

Détail du produit anti-ACVR2B anticorps

Antigène: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Épitope: Extracellular Domain

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVR2B est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Recognizes the extracellular domain of human and mouse ACTR-IIB.

Réactivité croisée: Humain, Souris

Réactivité croisée (Details): Does not cross-react with related human proteins ActR-IIecd, BMPR-IIecd, BMPR-IAecd, BMPR-IBecd or ActR-Iecd.

Purification: Antigen affinity purified.

Immunogène: Recombinant extracellular domain (ecd) of mouse activin receptor IIB.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS with 1 mg/mL BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur ACVR2B

Antigène: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Autre désignation: Activin Receptor IIB (ACVR2B Produits)

Synonymes: anticorps ACVR2B, anticorps XAR1, anticorps actr-iib, anticorps actriib, anticorps ACTRIIB, anticorps ActR-IIB, anticorps HTX4, anticorps ActRIIB, anticorps actr2b, anticorps actrIIb, anticorps wu:fj97d11, anticorps activin A receptor type 2B, anticorps activin A receptor type 2B L homeolog, anticorps activin A receptor type 2Ba, anticorps activin receptor IIB, anticorps ACVR2B, anticorps acvr2b, anticorps acvr2b.L, anticorps Acvr2b, anticorps acvr2ba

Sujet: Activin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary.

UniProt: P27040

Pathways: Hormone Transport, Cancer Immune Checkpoints