APAF1 anticorps (AA 12-28)
Aperçu rapide pour APAF1 anticorps (AA 12-28) (ABIN205853)
Antigène
Voir toutes APAF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 12-28
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Specificité
- Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. AHP487 recognizes a 130kD band in Western blots.
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Purification
- Affinity purified
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Immunogène
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Synthetic peptide corresponding to amino acids 12-28 of human Apaf1 ( AA 12-28 ).
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Indications d'application
- Approved: IHC, IHC-P, WB (1:1000 - 1:2000)
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Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. Store undiluted.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
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Autre désignation
- APAF1 / APAF-1
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Sujet
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Name/Gene ID: APAF1
Family: Apoptosis
Synonyms: APAF1, APAF-1, CED4, KIAA0413 -
ID gène
- 317
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UniProt
- O14727
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Pathways
- Signalisation p53, Apoptose, Caspase Cascade in Apoptosis, Tube Formation, Positive Regulation of Endopeptidase Activity
Antigène
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