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ATF2 anticorps (pThr53, pThr71)

L’anticorps anti-ATF2 Polyclonal Lapin est utilisé pour la détection de ATF2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IP et IHC (p).
N° du produit ABIN317966
723,08 €
Plus frais de livraison 40,00 € et TVA
0.1 mg
Destination: France
Envoi sous 17 jours ouvrables

Aperçu rapide pour ATF2 anticorps (pThr53, pThr71) (ABIN317966)

Antigène

Voir toutes ATF2 Anticorps
ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivité

  • 341
  • 240
  • 207
  • 17
  • 12
  • 11
  • 8
  • 7
  • 7
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 368
  • 17
  • 1
  • 1
Lapin

Clonalité

  • 325
  • 62
Polyclonal

Conjugué

  • 174
  • 21
  • 11
  • 11
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 3
  • 3
  • 3
  • 2
Cet anticorp ATF2 est non-conjugé

Application

  • 289
  • 130
  • 121
  • 119
  • 118
  • 85
  • 85
  • 48
  • 41
  • 29
  • 23
  • 10
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 55
    • 45
    • 26
    • 25
    • 25
    • 24
    • 24
    • 23
    • 15
    • 15
    • 15
    • 15
    • 13
    • 11
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr53, pThr71

    Specificité

    P-ATF2 (pThr71/53) antibody detects endogenous levels of p-ATF2 protein.

    Purification

    Affinity chromatography
  • Indications d'application

    ELISA: 1: 20000approx. 1: 40000. Western Blot: 1: 500approx. 1: 1000. Immunohistochemistry: 1: 50approx. 1: 200. Immunoprecipitation: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1,0 mg/mL

    Buffer

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    ATF2 (Activating Transcription Factor 2 (ATF2))

    Autre désignation

    ATF2

    Sujet

    Eukaryotic gene transcription is regulated by sequence-specific transcription factors which bind modular CIS acting promotor and enhancer elements. The cAMP response element (CRE), one of the best studied of such elements, consists of the palindromic octanucleotide TGACGTCA. Several CRE binding proteins have been identified within the ATF/CREB family, the best characterized of which include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. These proteins share highly related COOH terminal leucine zipper dimerization and basic DNA binding domains but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins appear capable of binding CRE in its homodimeric form, certain of these also bind as heterodimers, both within the ATF/CREB family and even with members of the AP-1 transcription factor family.Synonyms: ATF-2, Activating transcription factor 2, CRE-BP1, CREB-2, CREB2, CREBP1, Cyclic AMP-dependent transcription factor ATF-2, Cyclic AMP-responsive element-binding protein 2, HB16, cAMP response element-binding protein CRE-BP1, cAMP-dependent transcription factor ATF-2

    ID gène

    1386

    NCBI Accession

    NP_001871

    UniProt

    P15336

    Pathways

    Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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