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ATP6V1A anticorps (AA 441-468)

Il existe 1 publication pour ce produit. L’anticorps anti-ATP6V1A Polyclonal Lapin est utilisé pour la détection de ATP6V1A dans des échantillons de Humain. Il a été validé pour WB et IHC (p).
N° du produit ABIN653735
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour ATP6V1A anticorps (AA 441-468) (ABIN653735)

Antigène

Voir toutes ATP6V1A Anticorps
ATP6V1A (ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))

Reactivité

  • 37
  • 11
  • 8
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 37
  • 5
Lapin

Clonalité

  • 35
  • 7
Polyclonal

Conjugué

  • 34
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp ATP6V1A est non-conjugé

Application

  • 36
  • 19
  • 15
  • 8
  • 8
  • 8
  • 5
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB24578
  • Épitope

    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 441-468

    Homologie

    B, M, Pig

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This ATP6V1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-468 amino acids from the Central region of human ATP6V1A.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Nabatov, Hatzis, Rouschop, van Diest, Vooijs: "Hypoxia inducible NOD2 interacts with 3-O-sulfogalactoceramide and regulates vesicular homeostasis." dans: Biochimica et biophysica acta, Vol. 1830, Issue 11, pp. 5277-86, (2013) (PubMed).

  • Antigène

    ATP6V1A (ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))

    Autre désignation

    ATP6V1A

    Sujet

    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues.

    Poids moléculaire

    68304

    ID gène

    523

    NCBI Accession

    NP_001681

    UniProt

    P38606

    Pathways

    Transition Metal Ion Homeostasis, Proton Transport, SARS-CoV-2 Protein Interactome
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