ERCC8 anticorps (C-Term)
(1 reference)Aperçu rapide pour ERCC8 anticorps (C-Term) (ABIN486848)
Antigène
Voir toutes ERCC8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- QELYSGSRDC NILAWVPSLY EPVPDDDETT TKSQLNPAFE DAWSSSDEEG
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Homologie
- Dog: 93%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 79%, Rat: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against ERCC8. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human ERCC8
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anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody
ERCC8 Reactivité: Humain, Rat, Chien, Lapin, Cheval, Porc WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (Center) antibodyERCC8 Reactivité: Humain, Souris, Rat WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (AA 1-396) antibodyERCC8 Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (Internal Region) antibodyERCC8 Reactivité: Humain, Souris WB, IF, ICC, Func Hôte: Lapin Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) antibodyERCC8 Reactivité: Humain WB, ICC, FACS Hôte: Lapin Monoclonal 23GB5905 unconjugated Recombinant Antibody
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (AA 161-260) antibodyERCC8 Reactivité: Humain, Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (AA 210-238) antibodyERCC8 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB20950 unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (AA 1-164) antibodyERCC8 Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (AA 1-396) antibodyERCC8 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (N-Term) antibodyERCC8 Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Porc, Cobaye, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 396 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Cumulative defects in DNA repair pathways drive the PARP inhibitor response in high-grade serous epithelial ovarian cancer cell lines." dans: Oncotarget, Vol. 8, Issue 25, pp. 40152-40168, (2018) (PubMed).
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- ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
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Autre désignation
- ERCC8
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Sujet
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ERCC8 (excision repair cross-complementing rodent repair deficiency, complementation group 8 isoform 1) is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcript
Alias Symbols: CKN1, CSA
Protein Interaction Partner: CUL4A, CUL4B, DDB1, RUVBL2, ZNF24, PCNA, H1F0, ERCC6, UVSSA, DDA1, RFWD2, COPS4, COPS6, COPS3, TOP1, TP53, SSBP1, OGG1, MDM2, GTF2H2, CUL5, GPS1, DDB2, COPS2, COPS7A, COPS5, COPS8, RBX1, POLR2A, HMGN1, EP300, UBC, CSNK2B, XAB2, UQCRQ, CBR1,
Protein Size: 396 -
Poids moléculaire
- 44 kDa
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ID gène
- 1161
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NCBI Accession
- NM_000082, NP_000073
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UniProt
- Q13216
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Pathways
- Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
Antigène
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