ERCC8 anticorps (AA 210-238)

N° du produit ABIN654909

Détail du produit anti-ERCC8 anticorps

Antigène: ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

Épitope: AA 210-238

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ERCC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human ERCC8.

Clone: RB20950

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ERCC8

Antigène: ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

Autre désignation: ERCC8 (ERCC8 Produits)

Synonymes: anticorps zgc:103550, anticorps CKN1, anticorps CSA, anticorps UVSS2, anticorps Ckn1, anticorps 2410022P04Rik, anticorps 2810431L23Rik, anticorps 4631412O06Rik, anticorps B130065P18Rik, anticorps Csa, anticorps excision repair cross-complementation group 8, anticorps ERCC excision repair 8, CSA ubiquitin ligase complex subunit, anticorps excision repaiross-complementing rodent repair deficiency, complementation group 8, anticorps ercc8, anticorps ERCC8, anticorps Ercc8

Sujet: This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Poids moléculaire: 44055

ID gène: 1161

NCBI Accession: NP_000073

UniProt: Q13216

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus