ERCC8 anticorps (Internal Region)

N° du produit ABIN2857082

Détail du produit anti-ERCC8 anticorps

Antigène: ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Functional Studies (Func)

Attributs du produit: Rabbit Polyclonal antibody to ERCC8 (excision repair cross-complementing rodent repair deficiency, complementation group 8)
ERCC8 antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ERCC8. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Functional Assay Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000* Functional AssayAssay-dependent dilution

Commentaires:

Positive Control: 293T , A431 , Neuro2A , GL261 , C8D30 , NIH-3T3, Raw264.7 , C2C12

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ERCC8

Antigène: ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

Autre désignation: ERCC8 (ERCC8 Produits)

Synonymes: anticorps zgc:103550, anticorps CKN1, anticorps CSA, anticorps UVSS2, anticorps Ckn1, anticorps 2410022P04Rik, anticorps 2810431L23Rik, anticorps 4631412O06Rik, anticorps B130065P18Rik, anticorps Csa, anticorps excision repair cross-complementation group 8, anticorps ERCC excision repair 8, CSA ubiquitin ligase complex subunit, anticorps excision repaiross-complementing rodent repair deficiency, complementation group 8, anticorps ercc8, anticorps ERCC8, anticorps Ercc8

Sujet: This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

Cellular Localization: Nucleus

Poids moléculaire: 44 kDa

ID gène: 1161

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus