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FGFR3 anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement FGFR3 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.
N° du produit ABIN391969
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour FGFR3 anticorps (C-Term) (ABIN391969)

Antigène

Voir toutes FGFR3 Anticorps
FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reactivité

  • 154
  • 70
  • 50
  • 4
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 134
  • 12
  • 10
  • 1
  • 1
Lapin

Clonalité

  • 100
  • 58
Polyclonal

Conjugué

  • 58
  • 13
  • 9
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp FGFR3 est non-conjugé

Application

  • 101
  • 48
  • 45
  • 29
  • 25
  • 19
  • 13
  • 13
  • 11
  • 9
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB01572
  • Épitope

    • 32
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 776-806, C-Term

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogène

    This FGFR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 776-806 amino acids from the C-terminal region of human FGFR3.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Antigène

    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

    Autre désignation

    FGFR3

    Sujet

    FGFR3 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.

    Poids moléculaire

    87710

    ID gène

    2261

    NCBI Accession

    NP_000133, NP_001156685, NP_075254

    UniProt

    P22607

    Pathways

    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
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