IGF1R anticorps (pTyr1166)
(1 reference)Aperçu rapide pour IGF1R anticorps (pTyr1166) (ABIN362039)
Antigène
Voir toutes IGF1R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr1166
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Specificité
- The antibody detects endogenous level of IGF-1R only when phosphorylated at tyrosine 1165/tyrosine1166.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
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Immunogène
- Peptide sequence around phosphorylation site of pTyr 1165, pTyr1166 (T-D-Y (p) -Y (p) -R-K) derived from Human IGF-1R . Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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Isotype
- IgG
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anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 251-350) antibody
IGF1R Reactivité: Humain, Souris, Rat, Chien FACS Hôte: Lapin Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1346) antibodyIGF1R Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1165), (pTyr1166) antibodyIGF1R Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1161) antibodyIGF1R Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77) antibodyIGF1R Reactivité: Humain WB, IHC, ELISA, FACS, IF Hôte: Lapin Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1335-1366), (C-Term) antibodyIGF1R Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal RB01458 unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77), (N-Term) antibodyIGF1R Reactivité: Humain WB, FACS, IF, IHC (p) Hôte: Lapin Polyclonal RB15292 unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 660-760) antibodyIGF1R Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (C-Term) antibodyIGF1R Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 19-51), (N-Term) antibodyIGF1R Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB1455-1456 unconjugated
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Indications d'application
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "WITHDRAWN: Glutamate Attenuates IGF-1 Receptor Signaling via NR2B containing NMDA Receptors 3 and neuronal Nitric Oxide Synthase." dans: Biochemical and biophysical research communications, (2011) (PubMed).
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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Autre désignation
- IGF-1R
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Sujet
- This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
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Poids moléculaire
- 95 kDa
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NCBI Accession
- NP_000866
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UniProt
- P08069
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Pathways
- Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
Antigène
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