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ITPR1 anticorps (AA 1892-1911)

Cet anticorps anti-ITPR1 Polyclonal Lapin (ABIN337359) détecte spécifiquement ITPR1 dans IHC, WB, IP, ICC, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache) et Singe.
N° du produit ABIN337359
639,37 €
Plus frais de livraison 40,00 € et TVA
50 μL
Destination: France
Envoi sous 15 à 20 jours ouvrables

Aperçu rapide pour ITPR1 anticorps (AA 1892-1911) (ABIN337359)

Antigène

Voir toutes ITPR1 Anticorps
ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Reactivité

  • 54
  • 35
  • 31
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Rat, Souris, Boeuf (Vache), Singe

Hôte

  • 52
  • 9
Lapin

Clonalité

  • 47
  • 15
Polyclonal

Conjugué

  • 40
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ITPR1 est non-conjugé

Application

  • 28
  • 26
  • 22
  • 14
  • 9
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    • 12
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1892-1911

    Specificité

    Recognizes human IP3R-I. Detects a band of ~240kD by Western Blot. Species cross-reactivity: mouse, rat and canine.

    Homologie

    Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine (100%) Hamster, Elephant, Panda, Horse (95%) Opossum (85%).

    Purification

    Affinity purified

    Immunogène

    Synthetic peptide corresponding to aa 1892-1911 (N1892KKKDDEVDRDAPSRKKAKE1911) of the cytoplasmic C-terminal domain of human IP3R-I (inositol 1,4,5-triphosphate receptor (type-I)). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine (100%), Hamster, Elephant, Panda, Horse (95%), Opossum (85%).

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG
  • Indications d'application

    Approved: ICC, IHC, IHC-Fr (1:125), IHC-P (5 μg/mL), IP, WB (1:500)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 1 mg/mL BSA, 0.05 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    4°C or -20°C, Avoid freeze-thaw cycles.
  • Antigène

    ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

    Autre désignation

    ITPR1 / IP3 Receptor Type 1

    Sujet

    Name/Gene ID: ITPR1
    Subfamily: Inositol 1,4,5-triphosphate receptor
    Family: Ion Channel

    Synonyms: ITPR1, InsP3R-I, IP3R1, InsP3R, InsP3R type I, INSP3R1, IP3R, Opisthotonus, Pcp1, IP3 receptor, IP3 receptor isoform 1, SCA15, Spinocerebellar ataxia 15, Spinocerebellar ataxia 16, I145TR, IP3R 1, KIAA1754, SCA16, Type 1 InsP3 receptor

    ID gène

    3708

    Pathways

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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