Paxillin anticorps (pTyr31)
Aperçu rapide pour Paxillin anticorps (pTyr31) (ABIN196941)
Antigène
Voir toutes Paxillin (PXN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr31
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Specificité
- Paxillin antibody detects endogenous levels of Paxillin only when phosphorylated at tyrosine 31.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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Immunogène
- The antiserum was produced against synthesized phosphopeptide derived from human Paxillin around the phosphorylation site of tyrosine 31 (T-P-YP-S-Y).
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anti-Paxillin (PXN) (AA 347-578) antibody
PXN Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Paxillin (PXN) (AA 201-461) antibodyPXN Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Paxillin (PXN) (AA 1-262) antibodyPXN Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated
anti-Paxillin (PXN) (AA 327-568) antibodyPXN Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Paxillin (PXN) (AA 9-570) antibodyPXN Reactivité: Humain, Souris, Rat WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated
anti-Paxillin (PXN) (AA 456-472) antibodyPXN Reactivité: Humain, Souris, Rat WB, IF, ICC, IHC (p), FACS, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Paxillin (PXN) antibodyKD Validated PXN Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB2690 unconjugated Recombinant Antibody
anti-Paxillin (PXN) (AA 1-557) antibodyPXN Reactivité: Humain, Souris, Rat, Poulet, Chien WB, IHC, IF, IP Hôte: Souris Monoclonal 165-Paxillin unconjugated
anti-Paxillin (PXN) (AA 456-472), (C-Term) antibodyPXN Reactivité: Humain, Souris, Rat WB, IHC, IF, ICC, FACS, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Paxillin (PXN) (AA 1-262) antibodyPXN Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western Blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS(without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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- Paxillin (PXN)
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Autre désignation
- Paxillin / PXN
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Sujet
- Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).Synonyms: FLJ16691
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ID gène
- 5829
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NCBI Accession
- NP_001074324
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UniProt
- P49023
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Pathways
- Signalisation MAPK, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Antigène
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