GLUT4 anticorps (AA 401-509)
Aperçu rapide pour GLUT4 anticorps (AA 401-509) (ABIN739445)
Antigène
Voir toutes GLUT4 (SLC2A4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 401-509
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Réactivité croisée
- Chévre, Humain, Souris, Porc, Rat, Mouton
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Homologie
- Dog,Cow,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human GLUT4
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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: "High Fat Diet Upregulates Fatty Acid Oxidation and Ketogenesis via Intervention of PPAR-γ." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 48, Issue 3, pp. 1317-1331, (2018) (PubMed).
: "Effects of isoleucine on glucose uptake through the enhancement of muscular membrane concentrations of GLUT1 and GLUT4 and intestinal membrane concentrations of Na+/glucose co-transporter 1 (SGLT-1) ..." dans: The British journal of nutrition, Vol. 116, Issue 4, pp. 593-602, (2016) (PubMed).
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- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
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Autre désignation
- GLUT4
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Sujet
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Synonyms: GLUT4, Solute carrier family 2, facilitated glucose transporter member 4, Glucose transporter type 4, insulin-responsive, GLUT-4, SLC2A4
Background: GLUT4 is the facilitated glucose transporter expressed exclusively in adipocytes and muscle cells, and is also known as the "insulin-responsive" glucose transporter. GLUT4 translocates from an ill-defined intracellular compartment to the plasma membrane in response to insulin. The total cellular content of GLUT4 is significantly decreased in adipose cells from many patients with Type II diabetes mellitus, and animals with some types of experimental diabetes.
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ID gène
- 6517
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UniProt
- P14672
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Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, L'effet Warburg
Antigène
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