GLUT4 anticorps (N-Term)

N° du produit ABIN2781558

Cet anticorps Lapin Polyclonal détecte spécifiquement GLUT4 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Boeuf (Vache), Chévre, Cheval, Chien, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour GLUT4 anticorps (N-Term) (ABIN2781558)

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chévre, Cheval, Chien, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLUT4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GLUT4 anticorps

Épitope: N-Term

Séquence: LQFGYNIGVI NAPQKVIEQS YNETWLGRQG PEGPSSIPPG TLTTLWALSV

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SLC2A4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC2A4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 509 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GLUT4

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Autre désignation: SLC2A4

Sujet: SLC2A4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus.This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GLUT4
Protein Interaction Partner: UBC, FAR1, P3H1, FKBP10, ESYT2, GNL3L, CRNKL1, STRN3, ARFIP1, SDF2L1, P3H4, KLHL41, PDIA6, MVP, RAB7A, UBE2N, PSMD7, PRKAR1A, NSF, IDH1, HSP90AA1, HK2, GAPDH, DLD, CTSD, SERPINH1, BSG, ARF5, ARF3, ACTN1, ACTN4, ACOX1, DSK2, UBI4, C1QTNF5, MAP1S, EHD2, UBE
Protein Size: 509

Poids moléculaire: 55 kDa

ID gène: 6517

NCBI Accession: NM_001042, NP_001033

UniProt: P14672

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, L'effet Warburg