CD11b anticorps
Aperçu rapide pour CD11b anticorps (ABIN135134)
Antigène
Voir toutes CD11b (ITGAM) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Rat Anti-Mouse CD11b-LE/AF
-
Specificité
- Mouse CD11b, Mr 170 kDa
-
Attributs du produit
- Low Endotoxin/Azide Free Anti-Mouse CD11b antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
-
niveau d'endotoxine
- Low Endotoxin
-
Immunogène
- Peritoneal macrophages from B6D2 hybrid mice
-
Isotype
- IgG2a
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Phosphate buffered saline, pH 7.4
-
Agent conservateur
- Azide free
-
Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
-
Stock
- 4 °C
-
Stockage commentaire
- 2-8°C
-
-
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
-
Autre désignation
- CD11b
-
Sujet
- CD11b (integrin M subunit) combines with CD18 (integrin 2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
-
ID gène
- 16409
-
UniProt
- P05555
-
Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Antigène
-