anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Anticorps

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (21) et ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 280 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-ABCB1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>NCI-H226 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Connectez-vous pour afficher 1 to 2 Days
$139.00
Détails
Humain Lapin Inconjugué IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$200.00
Détails
Chien Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 12 to 15 Days
$636.30
Détails
Humain Souris Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$430.10
Détails
Humain Souris Inconjugué IHC (fro), IF, IHC (p), WB   0.1 mg Connectez-vous pour afficher 6 to 8 Days
$313.50
Détails
Humain Souris Inconjugué IHC (p), WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Humain Lapin Inconjugué IHC (p) Anti-ABCB1 / MDR1 antibody  ABIN1048283 IHC staining of human kidney, proximal convoluted tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Hamster Lapin Inconjugué IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$676.50
Détails
Humain Souris Inconjugué FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Connectez-vous pour afficher 6 to 8 Days
$346.50
Détails

ABCB1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps mieux référencés

  1. Human Polyclonal ABCB1 Primary Antibody pour IHC (fro), IHC (p) - ABIN3043967 : Gao, Liu, Wang, Lin, Zhang: Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells. dans Medical oncology (Northwood, London, England) 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ABCB1 Primary Antibody pour ICC, IHC (fro) - ABIN3043101 : Wang, Deng, Lu, Xu, Yan, Ye, Chen et al.: Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 ... dans Basic & clinical pharmacology & toxicology 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal ABCB1 Primary Antibody pour ELISA, WB - ABIN1724923 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. dans Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal ABCB1 Primary Antibody pour ELISA, WB - ABIN1724927 : Rubi?, Ho?ysz, Barczak, Gryczka, ?aci?ski, Jagielski, Czernikiewicz, Pó?rolniczak, Wojewoda, Perz, Bia?ek, Morze, Kandu?a, Lisiak, Mrozikiewicz, Grodecka-Gazdecka, Rybczy?ska: Study of ABCB1 polymorphism frequency in breast cancer patients from Poland. dans Pharmacological reports : PR 2013 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal ABCB1 Primary Antibody pour IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. dans Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal ABCB1 Primary Antibody pour FACS - ABIN2479421 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. dans Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal ABCB1 Primary Antibody pour FACS - ABIN2479422 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... dans Cancer research 1996 (PubMed)
    Show all 4 Pubmed References

  8. Human Monoclonal ABCB1 Primary Antibody pour IHC (fro), FACS - ABIN2479419 : Koziolek, Riess, Geiger, Thévenod, Hauser: Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. dans Kidney international 2001 (PubMed)
    Show all 4 Pubmed References

  9. Human Monoclonal ABCB1 Primary Antibody pour FACS - ABIN2479424 : Park, Lomri, Simeoni, Fruehauf, Mechetner: Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. dans Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003 (PubMed)
    Show all 4 Pubmed References

  10. Hamster Monoclonal ABCB1 Primary Antibody pour FACS, ICC - ABIN4333365 : Kurihara, Sato, Akimoto, Ogura, Ito: Identification and characterization of ABCB1-mediated and non-apoptotic sebum secretion in differentiated hamster sebocytes. dans Biochimica et biophysica acta 2011 (PubMed)

Plus d’anticorps contre ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 partenaires d’interaction

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (Montrer ABCB4 Anticorps), Bcrp (Montrer ABCG2 Anticorps) and Mrp1 (Montrer ABCC1 Anticorps) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (Montrer ABCB4 Anticorps)--{REVIEW}

  2. Studied ABCB1 protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1-expressing neurons in the left habenula.

  3. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (Montrer ABCC6 Anticorps), ABCB1 and CYP2C8 (Montrer CYP2C8 Anticorps) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

  4. The authors found that transient TUBB3 (Montrer TUBB3 Anticorps) activation, through ABCB1, in response to the stimulation of FOXO3a (Montrer FOXO3 Anticorps) expression, significantly contributes to the cross-resistance of the paclitaxel-resistant cell population and consequently limits the efficacy of both agents where cancer cells have developed multiple resistance.

  5. MDR1 (Montrer TBC1D9 Anticorps) and CYP3A5 (Montrer CYP3A5 Anticorps) genetic polymorphisms significantly influence plasma trough levels and therapeutic response of imatinib in patients with chronic myeloid leukemia (Montrer BCL11A Anticorps). Patients with GG genotype for CYP3A5 (Montrer CYP3A5 Anticorps)-A6986G (P=0.016) and TT genotype for MDR1 (Montrer TBC1D9 Anticorps)-C3435T (P=0.013) polymorphisms had significantly higher trough levels of imatinib.

  6. Rescue experiments confirmed the combined role of LUCAT1, miR (Montrer MLXIP Anticorps)-200c and ABCB1 on osteosarcoma proliferation, invasion and methotrexate resistance. Overall, results indicate the vital role of LUCAT1 in the methotrexate resistance regulation through miR (Montrer MLXIP Anticorps)-200c/ABCB1 pathway, providing a novel insight and treatment strategy for osteosarcoma drug resistance.

  7. Mdr1 (Montrer TBC1D9 Anticorps) enforces T Cell homeostasis in the presence of intestinal bile acids.

  8. Data show that co-treated with vincristine and XL019, a inhibitor of JAK2 and P-glycoprotein (P-gp), up-regulated expression of p21 and phosphorylated H2A histone family, member X (pH2AX).

  9. Tangeretin could sensitize ABCB1-overexpressing cancer cells to chemotherapeutical agents by directly inhibiting ABCB1 transporter function.

  10. over-functional P-gp (Montrer ABCB4 Anticorps) might play an important role in the pathogenesis of ITP (Montrer ITPA Anticorps) and induce GCs (Montrer GCLC Anticorps) resistance in nonresponsive ITP (Montrer ITPA Anticorps) patients. The blockage of P-gp (Montrer ABCB4 Anticorps) could be a promising therapeutic approach for GCs (Montrer GCLC Anticorps)-resistant patients with ITP (Montrer ITPA Anticorps).

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. conclusion, MDR1 (Montrer ABCB4 Anticorps) and BCRP (Montrer ABCG2 Anticorps) are expressed on apical membranes of the rodent placental SynT (Montrer STX1A Anticorps)-II layer.

  2. Mdr1 (Montrer ABCB4 Anticorps) enforces T Cell homeostasis in the presence of intestinal bile acids.

  3. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  4. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (Montrer ABCB4 Anticorps) ATPase (Montrer DNAH8 Anticorps) activity

  5. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  6. Chrysosplenetin inhibited P-gp (Montrer ABCB4 Anticorps) activity and reverse the up-regulated P-gp (Montrer ABCB4 Anticorps) and MDR1 (Montrer ABCB4 Anticorps) levels induced by artemisinin.

  7. Tamsulosin and tolterodine with P-gp (Montrer ABCB4 Anticorps) gene expression and activity in an enantiomer-specific way.

  8. Pgp (Montrer ABCB4 Anticorps)-coupled ATPase (Montrer DNAH8 Anticorps) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  9. Data show that human transgenic mutant huntingtin (Montrer HTT Anticorps) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (Montrer ABCB4 Anticorps)) which suggests that MDR1 (Montrer ABCB4 Anticorps) might be a potential therapeutic target for Huntington's disease.

  10. In vitro and in vivo downregulation of the ATP binding cassette transporter (Montrer ABCC3 Anticorps) B1 by the HMG-CoA reductase (Montrer HMGCR Anticorps) inhibitor simvastatin

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) profil antigène

Profil protéine

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1) anticorps
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) anticorps
  • ATP binding cassette subfamily B member 1A (Abcb1a) anticorps
  • ATP binding cassette subfamily B member 1 (Abcb1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps
  • malic enzyme complex, mitochondrial (Mod2) anticorps
  • ABC20 anticorps
  • ABCB1 anticorps
  • Cd243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • Mdr anticorps
  • Mdr-1 anticorps
  • Mdr1 anticorps
  • Mdr1a anticorps
  • Mdr1b anticorps
  • Mod-2 anticorps
  • Mod-2r anticorps
  • Mod-2s anticorps
  • Mod2-r anticorps
  • Mod2-s anticorps
  • p-gp anticorps
  • PGP1 anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps
  • xemdr anticorps

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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