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Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. De plus, nous expédions ACIN1 Protéines (3) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal ACIN1 Primary Antibody pour WB - ABIN264987
Zamzami, Kroemer: Condensed matter in cell death. dans Nature 1999
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Human Polyclonal ACIN1 Primary Antibody pour IF, WB - ABIN319023
Sahara, Aoto, Eguchi, Imamoto, Yoneda, Tsujimoto: Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation. dans Nature 1999
Genome-wide identification of RNA targets of Acinus revealed its role in splicing regulation as well as its involvement in other cellular pathways, including cell cycle progression.
acinus L was identified as a potential novel mTORC1 target.
Differences in the nuclear localization of Acinus-S' and Acinus-L may suggest that these two isoforms have different functional roles.
the ligand-dependent splicing activity of Acinus is related to the retinoic acid-activated retinoic acid receptor (Montrer RARA Anticorps)
An electronegative region on acinusS restricts SRPK2 (Montrer SRPK2 Anticorps) phosphorylation to a single specific site.
Chronic low-dose radiation increases the levels of AKT (Montrer AKT1 Anticorps) and acinus proteins via NF-kappaB (Montrer NFKB1 Anticorps) activation
Akt (Montrer AKT1 Anticorps) phosphorylation of acinus on serine 422 and 573 results in its resistance to caspase (Montrer CASP3 Anticorps) cleavage in the nucleus and the inhibition of acinus-dependent chromatin condensation.
Acinus is not involved in DNA condensation but rather has a role in internucleosomal DNA cleavage during programmed cell death
We found hypermethylation of the ACIN1 gene in early stage lung adenocarcinoma. The role of methylation status in the development and malignant transformation of lung adenocarcinoma requires clarification.
identify Acinus-S' as a novel RAR (Montrer RARA Anticorps)-interacting protein[Acinus-S']
gp70 (Montrer EMB Anticorps) enhances cellular DNA-damage-induced signaling in association with host-specific cellular proteins including acinus and MCM2 (Montrer MCM2 Anticorps) resulting in the activation of DNA-PK to phosphorylate P53 (Montrer TP53 Anticorps).
Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
apoptotic chromatin condensation inducer in the nucleus, b
, apoptotic chromatin condensation inducer in the nucleus, a
, apoptotic chromatin condensation inducer 1
, apoptotic chromatin condensation inducer in the nucleus
, apoptotic chromatin condensation inducer in the nucleus-like
, functional spliceosome-associated protein 152