anti-Cardiac Troponin C (TNNC1) Anticorps

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. De plus, nous expédions TNNC1 Protéines (18) et TNNC1 Kits (11) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TNNC1 7134 P63316
TNNC1 290561  
TNNC1 21924 P19123
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-TNNC1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 98 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (p), WB Anti-cardiac Troponin C antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$200.00
Détails
Cat Souris Inconjugué IHC (p), ELISA, WB Anti-TNNC1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104746 concentration 10 ug/ml. 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Humain Souris Inconjugué EIA, IHC (p), WB 50 μg Connectez-vous pour afficher 6 to 8 Days
$368.50
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB 50 μg Connectez-vous pour afficher 6 to 7 Days
$593.40
Détails
Humain Lapin Inconjugué ICC, IF Immunocytochemistry/Immunofluorescence: Troponin C (cardiac) Antibody  - Staining of human cell line HeLa shows localization to nucleoplasm, mitochondria & actin filaments. 100 μL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$676.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC (p), WB   100 μg Connectez-vous pour afficher 7 to 9 Days
$463.83
Détails
Humain Lapin Inconjugué IF, IHC, WB Western blot analysis of extracts of various cell lines, using TNNC1 antibody. 100 μL Connectez-vous pour afficher 16 Days
$334.02
Détails
Humain Souris Inconjugué ELISA (Detection), ELISA, WB   1 mg Connectez-vous pour afficher 5 to 7 Days
$383.72
Détails

TNNC1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , , , ,
,
,
, , , , ,
Rat (Rattus)
,
,
Mouse (Murine)
,
,

Plus d’anticorps contre TNNC1 partenaires d’interaction

Human Cardiac Troponin C (TNNC1) interaction partners

  1. Our results (i) confirm that genetic backgrounds of hypertrophic cardiomyopathy and restrictive cardiomyopathy overlap and (ii) indicate that TNNC1 is a likely novel gene for autosomal recessive restrictive cardiomyopathy.

  2. Data suggest that modulation of structural dynamics far from the regulatory Ca2 (Montrer CA2 Anticorps)+-binding site is the underlying molecular mechanism for many TNNC1 mutations in patients with hypertrophic cardiomyopathies or familial hypertrophic cardiomyopathies; many mutations affect balance between open and closed conformations; troponin I switch peptide [TnI (Montrer TNNI2 Anticorps)(SW)] switch peptide binds to TNNC1 and stabilizes the open TNNC1 conformation.

  3. Data suggest that mutations in troponin C (TnC (Montrer TNNC2 Anticorps)) found in patients with hypertrophic cardiomyopathy (A8V, C84Y, and D145E) stabilize the active state of regulated actin (the actin-tropomyosin (Montrer TPM2 Anticorps)-troponin complex) to various extents; at a saturating Ca2 (Montrer CA2 Anticorps)+ concentration, all TnC (Montrer TNC Anticorps) mutants investigated increase the level of active M state compared to the wild type.

  4. There was no difference in the test characteristics of the HEART Pathway whether using cTnI or hs-cTnI, with both achieving 100% sensitivity and NPV. Use of hs-cTnT with the HEART Pathway was associated with one missed major adverse cardiac events.

  5. contractility is constantly above normal in hearts made hypertrophic by TnC (Montrer TNC Anticorps) with the A8V mutation

  6. We used nuclear magnetic resonance and circular dichroism to solve the structure and characterize the backbone dynamics and stability of the regulatory domain of cTnC with the L29Q mutation.

  7. conclusive evidence that TNNC1 is an uncommon but definitive HCM-susceptibility gene

  8. Troponin C (TnC) and the N-terminal helix of Troponin I (TnI N-helix), which occurs in vivo during muscle contraction.

  9. FAK (Montrer PTK2 Anticorps)/CREB (Montrer CREB1 Anticorps)/TNNC1 has a role in mediating the effect of stromal MFAP5 (Montrer MFAP5 Anticorps) on ovarian cancer metastatic potential

  10. Mutations in cTnC have been associated with hypertrophic or dilated cardiomyopathy.[review]

Cow (Bovine) Cardiac Troponin C (TNNC1) interaction partners

  1. These results demonstrate that the L29Q mutation enhances the Ca(2+)-binding characteristics of cTnC and that when incorporated into cardiac myocytes, this mutant alters myocyte contractility.

Mouse (Murine) Cardiac Troponin C (TNNC1) interaction partners

  1. Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle.

  2. A region in cTnC associated with increased Ca(2 (Montrer CA2 Anticorps)+) sensitivity in skinned fibers was identified, an the F27W reporter mutation affected Ca(2 (Montrer CA2 Anticorps)+) sensitivity, maximal force, and ATPase (Montrer DNAH8 Anticorps) activation of some mutants.

  3. Overexpression of sTnC (Montrer TNNC2 Anticorps) polypeptide in muscle cells is controlled by its rapid degradation.

  4. These results demonstrate that the L29Q mutation enhances the Ca(2+)-binding characteristics of cTnC and that when incorporated into cardiac myocytes, this mutant alters myocyte contractility.

TNNC1 profil antigène

Profil protéine

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase\; TnT, which contains the binding site for tropomyosin\; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Gene names and symbols associated with TNNC1

  • troponin C type 1 (slow) L homeolog (tnnc1.L) anticorps
  • cardiac troponin C (tnnc1) anticorps
  • troponin C1, slow skeletal and cardiac type (TNNC1) anticorps
  • troponin C1, slow skeletal and cardiac type (Tnnc1) anticorps
  • troponin C, cardiac/slow skeletal (Tnnc1) anticorps
  • AI874626 anticorps
  • CMD1Z anticorps
  • CMH13 anticorps
  • cTnC anticorps
  • cTnI anticorps
  • MGC80066 anticorps
  • PCTNC1 anticorps
  • TN-C anticorps
  • TnC anticorps
  • tncc anticorps
  • TNNC anticorps
  • TNNC1 anticorps

Protein level used designations for TNNC1

cardiac troponin C , slow twitch skeletal/cardiac muscle troponin C , troponin C, slow skeletal and cardiac muscles , troponin C1, slow , troponin C, cardiac/slow skeletal , TN-C , Troponin C, slow skeletal and cardiac muscles

GENE ID SPECIES
379410 Xenopus laevis
399104 Xenopus laevis
7134 Homo sapiens
290561 Rattus norvegicus
396032 Gallus gallus
100156435 Sus scrofa
509486 Bos taurus
21924 Mus musculus
100347570 Oryctolagus cuniculus
Fournisseurs de qualité sélectionnés pour anti-TNNC1 (TNNC1) Anticorps
Avez-vous cherché autre chose?