Centromere Protein T (CENPT) Kits ELISA

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. De plus, nous expédions CENPT Anticorps (27) et CENPT Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CENPT 80152 Q96BT3
CENPT 320394 Q3TJM4
CENPT 307805 Q561R1
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Lapin 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
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Rat 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
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Souris 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
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Cobaye 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
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Chien 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
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Humain 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
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Singe 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
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Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 15 to 18 Days
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Plus Kits ELISA pour CENPT partenaires d'interaction

Xenopus laevis Centromere Protein T (CENPT) interaction partners

  1. These results support the existence of 2 pathways for kinetochore assembly directed by CENP-C (Montrer CENPC1 Kits ELISA) and CENP-T/W, which can be reconstituted in Xenopus egg extracts.

Human Centromere Protein T (CENPT) interaction partners

  1. Whereas CENP-C (Montrer CENPC1 Kits ELISA) recruits a single MIS12 (Montrer MIS12 Kits ELISA):NDC80 (Montrer NDC80 Kits ELISA) complex, the authors show here that CENP-T binds one MIS12 (Montrer MIS12 Kits ELISA):NDC80 (Montrer NDC80 Kits ELISA) and two NDC80 (Montrer NDC80 Kits ELISA) complexes upon phosphorylation by the mitotic CDK1 (Montrer CDK1 Kits ELISA):Cyclin B complex at three distinct CENP-T sites.

  2. FACT chaperone stabilizes the soluble CENP-T/-W complex in the cell and promotes dynamics of exchange, enabling CENP-T/-W deposition at centromeres.

  3. We used a synthetic system to dissect how CenH3(CENP-A (Montrer CENPA Kits ELISA)) contributes to the accumulation of CENP-C (Montrer CENPC1 Kits ELISA) and CENP-T, two key components that are necessary for the formation of functional kinetochores

  4. CENP-T directly interacts with Ndc80 (Montrer NDC80 Kits ELISA), which in turn promotes KNL1 (Montrer CASC5 Kits ELISA)/Mis12 (Montrer MIS12 Kits ELISA) complex recruitment at kinetochores during chromosome segregation.

  5. CSN5 regulates the stability of the inner kinetochore components CENP-T and CENP-W, providing the first direct link between CSN5 and the mitotic apparatus, highlighting the role of CSN5 as a multifunctional cell cycle regulator.

  6. CENP-T provides a structural platform for outer kinetochore assembly.

  7. results reveal the molecular function of CENP-T proteins and demonstrate how the Ndc80 (Montrer NDC80 Kits ELISA) complex is anchored to centromeres in a manner that couples chromosome movement to spindle dynamics

  8. The CENP-T/W complex assembles through a dynamic exchange mechanism in late S-phase and G2, is required for mitosis in each cell cycle and does not persist across cell generations.

  9. Study demonstrates that CENP-W (Montrer CENPW Kits ELISA) forms a DNA-binding complex together with the CCAN component CENP-T; this complex directly associates with nucleosomal DNA and with canonical histone H3 (Montrer HIST3H3 Kits ELISA), but not with CENP-A (Montrer CENPA Kits ELISA), in centromeric regions.

  10. CENP-T exchange into centromeres is restricted to the S-phase of the cell cycle as revealed by FRAP (Montrer FRAP1 Kits ELISA), suggesting a coreplicational loading mechanism.

CENPT profil antigène

Antigen Summary

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006

Gene names and symbols associated with Centromere Protein T (CENPT) Kits ELISA

  • centromere protein T (cenpt) anticorps
  • centromere protein T L homeolog (cenpt.L) anticorps
  • centromere protein T (CENPT) anticorps
  • si:ch211-225g23.1 (si:ch211-225g23.1) anticorps
  • centromere protein T (Cenpt) anticorps
  • C16orf56 anticorps
  • CENP-T anticorps
  • G630055P03Rik anticorps
  • MGC145722 anticorps
  • RGD1309383 anticorps
  • wu:fc31h11 anticorps
  • wu:fc75c05 anticorps

Protein level used designations for Centromere Protein T (CENPT) Kits ELISA

centromere protein T , centromere protein T-like , fc31h11 , fc75c05 , interphase centromere complex protein 22 , CENP-T

GENE ID SPECIES
779753 Xenopus (Silurana) tropicalis
100158304 Xenopus laevis
415654 Gallus gallus
454175 Pan troglodytes
562197 Danio rerio
100393620 Callithrix jacchus
80152 Homo sapiens
320394 Mus musculus
307805 Rattus norvegicus
611127 Canis lupus familiaris
513195 Bos taurus
101115894 Ovis aries
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