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CXCR7 encodes a member of the G-protein coupled receptor family. De plus, nous expédions CXCR7 Kits (11) et et beaucoup plus de produits pour cette protéine.
Showing 10 out of 136 products:
Human Monoclonal CXCR7 Primary Antibody pour FACS - ABIN2661157
Burns, Summers, Wang, Melikian, Berahovich, Miao, Penfold, Sunshine, Littman, Kuo, Wei, McMaster, Wright, Howard, Schall: A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. dans The Journal of experimental medicine 2006
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Human Polyclonal CXCR7 Primary Antibody pour EIA, IHC (fro) - ABIN492896
Tran, Miller: Chemokine receptors: signposts to brain development and disease. dans Nature reviews. Neuroscience 2003
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Human Polyclonal CXCR7 Primary Antibody pour EIA, IHC (p) - ABIN951737
Berahovich, Zabel, Penfold, Lewén, Wang, Miao, Gan, Pereda, Dias, Slukvin, McGrath, Jaen, Schall: CXCR7 protein is not expressed on human or mouse leukocytes. dans Journal of immunology (Baltimore, Md. : 1950) 2010
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Human Polyclonal CXCR7 Primary Antibody pour EIA, IHC (p) - ABIN453592
Sreedharan, Robichon, Peterson, Goetzl: Cloning and expression of the human vasoactive intestinal peptide receptor. dans Proceedings of the National Academy of Sciences of the United States of America 1991
Human Polyclonal CXCR7 Primary Antibody pour IF, ELISA - ABIN1535576
Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... dans Nature 2005
The scattershot allele results in an in-frame deletion of 8 amino acids at the junction of the third transmembrane domain and the second intracellular loop of Tre1 that dramatically impairs the function of this GPCR in germ cell migration.
plays an important role in regulation of germ cell migration, polarity , cell adhesion, and cadherin binding. (review)
Tre1 is a G protein-coupled receptor (Montrer GPBAR1 Anticorps) that directs transepithelial migration of Drosophila germ cells
Down-regulation of E-cadherin causes germ cell dispersal but is not sufficient for transepithelial migration in the absence of Tre1, suggesting a new mechanism for Tre1 GPCR function that links cell polarity, modulation of cell adhesion, and invasion.
CXCL12 (Montrer CXCL12 Anticorps) may be an effective diagnostic marker for papillary thyroid carcinoma, and CXCL12 (Montrer CXCL12 Anticorps)/CXCR4 (Montrer CXCR4 Anticorps)/CXCR7 axis may contribute to thyroid cancer development by regulating cancer cell migration and invasion via AKT (Montrer AKT1 Anticorps) and ERK (Montrer EPHB2 Anticorps) signaling and MMP-2 (Montrer MMP2 Anticorps) activation.
Our study suggested that CXCR7 plays an important proangiogenic role in hepatocellular carcinoma (HCC (Montrer FAM126A Anticorps)). via activation of the AKT (Montrer AKT1 Anticorps) pathway. So CXCR7 may be a potential target for antiangiogenic therapy in HCC (Montrer FAM126A Anticorps)
CXCR7 is a direct downstream target of miR (Montrer MLXIP Anticorps)-100, and overexpression of miR (Montrer MLXIP Anticorps)-100 efficiently suppresses CXCR7 expression.
Overexpression of CXCR7 is associated with breast cancer.
High CXCR7 expression is associated with endometrial cancer.
the current study revealed that CXCL12 (Montrer CXCL12 Anticorps) which combined its receptors CXCR4 (Montrer CXCR4 Anticorps) and CXCR7 together could promote cell migration and cell invasion of OSCC.
Increased CXCR7 expression is associated with invasion in nasopharyngeal carcinoma.
Up-regulation of miR (Montrer MLXIP Anticorps)-218 expression in renal cell carcinoma (Montrer MOK Anticorps) under hypoxia can result in significant and targeted down-regulation of CXCR7 expression.
CXCR7 affects the growth of PTC (Montrer F9 Anticorps) cells.
CXCR7 may play a role in the progression, metastasis and angiogenesis of otorhinolaryngologic tumours.
expression of CXCR7 in normal and pathological nervous system suggests CXCR4 (Montrer CXCR4 Anticorps)-independent functions of SDF-1/CXCL12 (Montrer CXCL12 Anticorps) mediated through its interaction with CXCR7
confirm a pivotal role of the SDF-1 (Montrer CXCL12 Anticorps)/CXCR4 (Montrer CXCR4 Anticorps)/CXCR7 axis for chronic allograft vasculopathy development
our present study provided evidence that SDF-1 (Montrer CXCL12 Anticorps) mediated CSCs migration through CXCR4 (Montrer CXCR4 Anticorps) and CXCR7 via MEK (Montrer MDK Anticorps)/ERK (Montrer EPHB2 Anticorps) and PI3K/Akt (Montrer AKT1 Anticorps) pathway
Endothelial CXCR7 limits breast cancer metastasis at multiple steps in the metastatic cascade, advancing understanding of CXCL12 (Montrer CXCL12 Anticorps) pathways in tumor environments and informing ongoing drug development targeting CXCR7 in cancer.
Sata demonstrate that CXCR7 has a role in the positioning of hem and pallium-subpallium boundary-derived Cajal-Retzius (CR)cells, CXCL12 (Montrer CXCL12 Anticorps) regulating CR cell subpial localization through the combined action of CXCR4 (Montrer CXCR4 Anticorps) and CXCR7.
CXCR7 acts to prevent epithelial damage and ameliorate fibrosis after a single lung injury, repeated injury leads to suppression of CXCR7 expression and recruitment of VEGFR1 (Montrer FLT1 Anticorps) expressing macrophages, Wnt (Montrer WNT2 Anticorps) and Notch (Montrer NOTCH1 Anticorps) signaling, and enhanced fibrosis.
CXCR7 overexpression in MSCs reversed the inhibitory effect of high concentrations of SDF-1alpha.
Collectively, our data demonstrate that CXCR7 suppression modulates microglial chemotaxis to ameliorate EAE.
Both CXCR7 and Rac1 are required for extracellular signal-regulated kinases (ERK) 1 (Montrer MAPK3 Anticorps)/2 activation and subsequent NPC (Montrer NPC1 Anticorps) migration, indicating that CXCR7 could serve as a functional receptor in CXCL12 (Montrer CXCL12 Anticorps)-mediated NPC (Montrer NPC1 Anticorps) migration independent of CXCR4 (Montrer CXCR4 Anticorps).
Blockade of CXCR7 suppressed MIF (Montrer MIF Anticorps)-mediated ERK (Montrer EPHB2 Anticorps)- and zeta-chain-associated protein kinase (Montrer CDK7 Anticorps) (ZAP)-70 (Montrer ZAP70 Anticorps) activation
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
, G protein coupled receptor
, trapped in endoderm 1
, trapped in endoderm-1
, C-X-C chemokine receptor type 7
, G protein-coupled receptor
, G-protein coupled receptor 159
, G-protein coupled receptor RDC1 homolog
, chemokine (C-X-C motif) receptor 7
, chemokine orphan receptor 1
, RDC1-like G protein-coupled receptor
, G-protein coupled receptor RDC1