Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Kits ELISA

CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. De plus, nous expédions CTLA4 Anticorps (451) et CTLA4 Protéines (85) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CTLA4 12477 P09793
CTLA4 1493 P16410
CTLA4 63835  
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Top CTLA4 Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 47 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.055 ng/mL 0.156-10 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
736,97 €
Détails
Souris 10pg/mL 156-10000 pg/mL Mouse CTLA4 PicoKine ELISA Kit standard curve 96 Tests Connectez-vous pour afficher 8 to 11 Days
475,62 €
Détails
Humain 0.33 ng/mL 0.78-50 ng/mL   96 Tests Connectez-vous pour afficher 6 to 8 Days
632,76 €
Détails
Rat 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
600,00 €
Détails
Poulet 0.938 ng/mL 1.563-100 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Lapin 0.938 ng/mL 1.563-100 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Cobaye 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 10 to 13 Days
666,67 €
Détails
Mouton
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails
Singe
  96 Tests Connectez-vous pour afficher 13 to 17 Days
673,47 €
Détails

CTLA4 Kits ELISA mieux référencés

  1. Mouse (Murine) CTLA4 Kit ELISA pour Sandwich ELISA - ABIN1672780 : Dariavach, Mattéi, Golstein, Lefranc: Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains. dans European journal of immunology 1989 (PubMed)

Plus Kits ELISA pour CTLA4 partenaires d'interaction

Mouse (Murine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. CTLA-4 expressed by FOXP3 (Montrer FOXP3 Kits ELISA)(+) regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis.

  2. results are consistent with a complex pathway in which CD28 (Montrer CD28 Kits ELISA) is the primary driver of Treg proliferation and CTLA-4 functions as the main brake but is also dependent on TCR signals and interactions with CD80 (Montrer CD80 Kits ELISA)/CD86 (Montrer CD86 Kits ELISA)

  3. CTLA-4(+) microvesicles can competitively bind B7 costimulatory molecules on bystander dendritic cells, resulting in downregulation of B7 surface expression.

  4. this study shows that miR (Montrer MLXIP Kits ELISA)-155 is modulated by a major dust mite allergen, Dermatophagoides farinae (Df1), and increases CD4 (Montrer CD4 Kits ELISA)+ T cell proliferation through the downregulation of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expression

  5. CTLA-4 regulates atherosclerosis by suppressing proatherogenic immune responses.

  6. Data suggest enhanced clinical benefit from combining CTLA-4 antigen blockade with poxvirus-based active immunotherapy.

  7. up-regulated expression correlates with the tolerogenic effect of syngeneic hematopoietic stem cell transplantation

  8. Induced Treg Cells Augment the Th17-Mediated Intestinal Inflammatory Response in a CTLA4-Dependent Manner

  9. CTLA-4 has a regulatory T cell-intrinsic role in limiting peripheral regulatory T cell expansion and activation, and in their capacity to control conventional T cells.

  10. The Ctla4 SNP (e2_77A/G) does not alter diabetes susceptibility, but does control mRNA alternative splicing.

Human Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. The CTLA-4 blockade may restore Th1 (Montrer TH1L Kits ELISA) function in patients with COPD (Montrer ARCN1 Kits ELISA) and so aid the clearance of bacterial pathogens responsible for acute exacerbations of chronic obstructive pulmonary disease.

  2. High CTLA4 expression is associated with head-and-neck squamous cell carcinoma.

  3. AUthors observed a significant correlation between the proportion of Tregs and (in)CTLA-4+ Tregs with IL-17A (Montrer IL17A Kits ELISA) concentration in clBALF. Data confirmed significant differences in the proportion of regulatory elements between cancerous lung and healthy lung and PB and the usefulness of BALF analysis in evaluation of immune response regulation in local lung cancer environment.

  4. CTLA-4 was expressed and functional on human breast cancer cells through influencing maturation and function of DCs in vitro, and CTLA-4 blockage not only recovered the antigen-presenting function of DCs and T-cells activation but also suppressed the biological activity of breast cancer cells themselves.

  5. For anti-CTLA4 therapy, there were no data retrievable on clinical efficacy. Although data on clinical efficacy of checkpoint inhibitors in metastatic bladder cancer are currently limited, the efficacy of these drugs might depend mainly on the metastatic volume and immune system integrity. Patients with PD-L1 (Montrer CD274 Kits ELISA) positive tumors and non-visceral metastases seem to derive the highest benefit from therapy.

  6. interpreting the functional significance of mutations in the CTLA-4 pathway identified by gene-sequencing approaches

  7. In multivariable analysis, patients receiving cord blood units with GG-CTLA4 genotype had poorer neutrophil recovery, increased non-relapse mortality, and inferior disease-free survival.

  8. CTLA-4(+) microvesicles can competitively bind B7 costimulatory molecules on bystander dendritic cells, resulting in downregulation of B7 surface expression.

  9. CTLA-4 +49 A/G polymorphism is not associated with Henoch-Schonlein purpura (HSP).

  10. Combined IL-21 (Montrer IL17C Kits ELISA)-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient

Pig (Porcine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Suggest a truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin as a novel approach for in vivo depletion of CD80 (Montrer CD80 Kits ELISA)-positive cells.

Cow (Bovine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. The surface expression of CTLA-4 was increased in subclinical stages of paratuberculosis infection while levels of ZAP-70 (Montrer ZAP70 Kits ELISA) were decreased in CD4 (Montrer CD4 Kits ELISA)+ T cells of both subclinical and clinical animals, indicating a change in T cell phenotype with disease state.

  2. These results suggested that the expression level of CTLA-4 in CD4 (Montrer CD4 Kits ELISA)-positive T cells has a potentially immunosuppressive function in bovine leukemia infection.

  3. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 (Montrer FOXP3 Kits ELISA) and CTLA4.

CTLA4 profil antigène

Antigen Summary

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Gene names and symbols associated with CTLA4

  • cytotoxic T-lymphocyte-associated protein 4 precursor (CTLA-4) anticorps
  • cytotoxic T-lymphocyte-associated protein 4 (CTLA4) anticorps
  • cytotoxic T-lymphocyte-associated protein 4 (LOC100222727) anticorps
  • cytotoxic T-lymphocyte-associated protein 4 (Ctla4) anticorps
  • CD anticorps
  • Cd152 anticorps
  • CELIAC3 anticorps
  • Ctla-4 anticorps
  • CTLA4 anticorps
  • GRD4 anticorps
  • GSE anticorps
  • IDDM12 anticorps
  • Ly-56 anticorps
  • sCTLA4 anticorps

Protein level used designations for CTLA4

cytotoxic T-lymphocyte-associated protein 4 precursor , CD152 protein , cytotoxic T-lymphocyte protein 4 , cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM , cytotoxic T-lymphocyte-associated protein 4 , costimulatory molecule B7 receptor , cytotoxic T lymphocyte-associated antigen 4 , CD152 antigen , cytotoxic T-lymphocyte-associated antigen 4 , CD152 isoform , celiac disease 3 , cytotoxic T lymphocyte associated antigen 4 short spliced form , cytotoxic T-lymphocyte antigen 4 , cytotoxic T-lymphocyte-associated serine esterase-4 , ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 , soluble form , transmembrane form , CTLA-4 , cytotoxic T lymphocyte-associated protein 4 , costimulatory molecule B7 receptor CD152

GENE ID SPECIES
443040 Ovis aries
705673 Macaca mulatta
100222727 Taeniopygia guttata
424106 Gallus gallus
470619 Pan troglodytes
493743 Felis catus
100126716 Papio anubis
12477 Mus musculus
1493 Homo sapiens
63835 Rattus norvegicus
100009412 Oryctolagus cuniculus
397286 Sus scrofa
403696 Canis lupus familiaris
281732 Bos taurus
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