Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Kits ELISA

CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. De plus, nous expédions CTLA4 Anticorps (468) et CTLA4 Protéines (83) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CTLA4 12477 P09793
CTLA4 1493 P16410
CTLA4 63835  
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Top CTLA4 Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 49 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.055 ng/mL 0.156-10 ng/mL 96 Tests Connectez-vous pour afficher 15 to 17 Days
$762.82
Détails
Souris 10pg/mL 156-10000 pg/mL Mouse CTLA4 PicoKine ELISA Kit standard curve 96 Tests Connectez-vous pour afficher 4 to 6 Days
$369.00
Détails
Rat 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$638.00
Détails
Humain 0.33 ng/mL 0.78-50 ng/mL   96 Tests Connectez-vous pour afficher 2 to 3 Days
$691.90
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Poulet 0.938 ng/mL 1.563-100 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Lapin 0.938 ng/mL 1.563-100 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Cobaye 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Boeuf (Vache)
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Souris 6 pg/mL 6.1 pg/mL - 1500 pg/mL   96 Tests Connectez-vous pour afficher 5 to 8 Days
$752.25
Détails

Plus Kits ELISA pour CTLA4 partenaires d'interaction

Rhesus Monkey Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Data show that CTLA-4(+)PD-1 (Montrer PDCD1 Kits ELISA)(-) memory CD4 (Montrer CD4 Kits ELISA)(+) T cells, which share phenotypic markers with regulatory T cells, were enriched in SIV DNA in blood, lymph nodes (LN), spleen, and gut (Montrer GUSB Kits ELISA), and contained replication-competent and infectious virus.

Mouse (Murine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Tregs were observed to regulate CD4 (Montrer CD4 Kits ELISA)(+), but not CD8 (Montrer CD8A Kits ELISA)(+), T cell infiltration into tumors through a CTLA-4/CD80 (Montrer CD80 Kits ELISA) dependent mechanism. Disrupting CTLA-4 interaction with CD80 (Montrer CD80 Kits ELISA) was sufficient to induce CD4 (Montrer CD4 Kits ELISA) T cell infiltration into tumors.

  2. These results suggest that CD44 (Montrer CD44 Kits ELISA)(+)CD117(+) T cells are stem cells and a specific T-cell phenotype that initially develops in the thymus, but they do not progress through DN3 and DN4 stages, lack a DP stage, and potently suppress T-cell proliferation and modulate the CTLA-4 pathway.

  3. data suggest that increased expression of checkpoint blockade molecules PD-1 (Montrer PDCD1 Kits ELISA) and CTLA-4 on donor T cells is not sufficient to prevent GvHD, and that cooperation between checkpoint blockade signaling by host cells and donor Tregs is necessary to limit GvHD in allo-HSCT recipients

  4. Treg cells expand in both humans and mice in blood-stage malaria and interfere with conventional T helper cell responses and follicular T helper (TFH)-B cell interactions in germinal centers. Mechanistically, Treg cells function in a critical temporal window to impede protective immunity through cytotoxic-T-lymphocyte-associated protein-4 (CTLA-4).

  5. CTLA-4 expressed by FOXP3 (Montrer FOXP3 Kits ELISA)(+) regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis.

  6. results are consistent with a complex pathway in which CD28 (Montrer CD28 Kits ELISA) is the primary driver of Treg proliferation and CTLA-4 functions as the main brake but is also dependent on TCR signals and interactions with CD80 (Montrer CD80 Kits ELISA)/CD86 (Montrer CD86 Kits ELISA)

  7. CTLA-4(+) microvesicles can competitively bind B7 costimulatory molecules on bystander dendritic cells, resulting in downregulation of B7 surface expression.

  8. this study shows that miR (Montrer MLXIP Kits ELISA)-155 is modulated by a major dust mite allergen, Dermatophagoides farinae (Df1), and increases CD4 (Montrer CD4 Kits ELISA)+ T cell proliferation through the downregulation of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expression

  9. CTLA-4 regulates atherosclerosis by suppressing proatherogenic immune responses.

  10. Data suggest enhanced clinical benefit from combining CTLA-4 antigen blockade with poxvirus-based active immunotherapy.

Human Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Tregs were observed to regulate CD4 (Montrer CD4 Kits ELISA)(+), but not CD8 (Montrer CD8A Kits ELISA)(+), T cell infiltration into tumors through a CTLA-4/CD80 (Montrer CD80 Kits ELISA) dependent mechanism. Disrupting CTLA-4 interaction with CD80 (Montrer CD80 Kits ELISA) was sufficient to induce CD4 (Montrer CD4 Kits ELISA) T cell infiltration into tumors.

  2. Our study reports a novel association of SNPs within CD86 (Montrer CD86 Kits ELISA) and CTLA4 genes with pemphigus. The CD86 (Montrer CD86 Kits ELISA) rs1129055 A allele appears to confer susceptibility to Pemphigus vulgaris (Montrer DSG3 Kits ELISA) but not to pemphigus foliaceus (Montrer DSG1 Kits ELISA).

  3. nasopharyngeal carcinoma patients with high tumor CTLA-4 expression had a poorer prognosis than those with low expression.

  4. CTLA-4 expressing Th17 cells may present regulatory activities in pancreatic cancer patients.

  5. Data show there was an independent negative prognostic impact of cytotoxic T lymphocyte associated antigen 4 (T-CTLA-4) expression in metastatic lymph nodes.

  6. High CTLA4 expression is associated with B-cell lymphoma.

  7. In this discovery cohort, the combination of PD-1 (Montrer PDCD1 Kits ELISA) and CTLA-4 emerged as the best predictor of response. Patients whose tumors had at least 20% of CD8 (Montrer CD8A Kits ELISA)+ T cells expressing these two markers had a median progression-free survival of 31.6 months, versus 9.6 months for patients with less than 20% of this subtype among their tumor CD8 (Montrer CD8A Kits ELISA)+ cells

  8. Review/Meta-analysis: CTLA-4 may not be a major susceptibility locus in humans with ankylosing spondylitis.

  9. Treg cells expand in both humans and mice in blood-stage malaria and interfere with conventional T helper cell responses and follicular T helper (TFH)-B cell interactions in germinal centers. Mechanistically, Treg cells function in a critical temporal window to impede protective immunity through cytotoxic-T-lymphocyte-associated protein-4 (CTLA-4).

  10. This review focuses on the pathogenesis, clinical manifestations and management of immune-related toxicity of anti-CTLA-4 and anti-PD-1 (Montrer PDCD1 Kits ELISA) antibodies

Pig (Porcine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. Suggest a truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin as a novel approach for in vivo depletion of CD80 (Montrer CD80 Kits ELISA)-positive cells.

Cow (Bovine) Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) interaction partners

  1. The surface expression of CTLA-4 was increased in subclinical stages of paratuberculosis infection while levels of ZAP-70 (Montrer ZAP70 Kits ELISA) were decreased in CD4 (Montrer CD4 Kits ELISA)+ T cells of both subclinical and clinical animals, indicating a change in T cell phenotype with disease state.

  2. These results suggested that the expression level of CTLA-4 in CD4 (Montrer CD4 Kits ELISA)-positive T cells has a potentially immunosuppressive function in bovine leukemia infection.

  3. Experimental infection with bovine viral diarrhea virus did not provide evidence ofTreg activation based on expression of FoxP3 (Montrer FOXP3 Kits ELISA) and CTLA4.

CTLA4 profil antigène

Antigen Summary

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Gene names and symbols associated with CTLA4

  • cytotoxic T-lymphocyte associated protein 4 (CTLA4) anticorps
  • cytotoxic T-lymphocyte-associated protein 4 (Ctla4) anticorps
  • CD anticorps
  • Cd152 anticorps
  • CELIAC3 anticorps
  • Ctla-4 anticorps
  • CTLA4 anticorps
  • GRD4 anticorps
  • GSE anticorps
  • IDDM12 anticorps
  • Ly-56 anticorps
  • sCTLA4 anticorps

Protein level used designations for CTLA4

cytotoxic T-lymphocyte-associated protein 4 precursor , CD152 protein , cytotoxic T-lymphocyte protein 4 , cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM , cytotoxic T-lymphocyte-associated protein 4 , costimulatory molecule B7 receptor , cytotoxic T lymphocyte-associated antigen 4 , CD152 antigen , cytotoxic T-lymphocyte-associated antigen 4 , CD152 isoform , celiac disease 3 , cytotoxic T lymphocyte associated antigen 4 short spliced form , cytotoxic T-lymphocyte antigen 4 , cytotoxic T-lymphocyte-associated serine esterase-4 , ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 , soluble form , transmembrane form , CTLA-4 , cytotoxic T lymphocyte-associated protein 4 , costimulatory molecule B7 receptor CD152

GENE ID SPECIES
443040 Ovis aries
705673 Macaca mulatta
100222727 Taeniopygia guttata
424106 Gallus gallus
470619 Pan troglodytes
493743 Felis catus
100126716 Papio anubis
12477 Mus musculus
1493 Homo sapiens
63835 Rattus norvegicus
100009412 Oryctolagus cuniculus
397286 Sus scrofa
403696 Canis lupus familiaris
281732 Bos taurus
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