CTLA4 Produits
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Catégories
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].
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Catégories CTLA4 en vedette
CTLA4 Anticorps
High quality antibodies with extensive validation data.
CTLA4 Kits ELISA
Reliable ELISA kits for a wide range of species.
CTLA4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CTLA4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
FACS
Validations
- (4)
- (4)
N° du produit
ABIN1981896
Quantité
100 tests
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (4)
N° du produit
ABIN514751
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
FACS, IP, ICC, IHC (fro)
Validations
- (3)
- (3)
N° du produit
ABIN1981873
Quantité
0.1 mg
Fiche technique
Fiche technique
CTLA4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966262
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955276
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1672780
Quantité
96 tests
Fiche technique
Fiche technique
CTLA4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (6)
N° du produit
ABIN7274436
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (7)
N° du produit
ABIN6961090
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7274435
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CTLA4
: "Immune signature as predictive marker for response to checkpoint inhibitor immunotherapy and overall survival in melanoma." dans: Cancer medicine, (2021) (PubMed).: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." dans: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).
: "Circulating CTLA-4 levels and CTLA4 polymorphisms associate with disease condition and progression and hepatocellular carcinoma patients' survival in chronic hepatitis B virus infection." dans: International immunopharmacology, Vol. 82, pp. 106377, (2020) (PubMed).
: "Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR." dans: mAbs, Vol. 12, Issue 1, pp. 1803646, (2020) (PubMed).
: "CTLA4-Ig Directly Inhibits Osteoclastogenesis by Interfering With Intracellular Calcium Oscillations in Bone Marrow Macrophages." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, (2019) (PubMed).
: "Revealing the atomistic details behind the binding of B7-1 to CD28 and CTLA-4: A comprehensive protein-protein modelling study." dans: Biochimica et biophysica acta. General subjects, Vol. 1862, Issue 12, pp. 2764-2778, (2019) (PubMed).
: "Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models." dans: American journal of cancer research, Vol. 9, Issue 1, pp. 53-63, (2019) (PubMed).
: "Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy." dans: Nature communications, Vol. 10, Issue 1, pp. 3850, (2019) (PubMed).
: "Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques." dans: PLoS pathogens, Vol. 15, Issue 9, pp. e1008015, (2019) (PubMed).
: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." dans: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à CTLA4
cytotoxic T-lymphocyte associated protein 4 (CTLA4), cytotoxic T-lymphocyte-associated protein 4 (Ctla4), CD, CD152, Cd152, CELIAC3, CTLA-4, Ctla-4, CTLA4, GRD4, GSE, IDDM12, Ly-56, sCTLA4Protein level used designations for CTLA4
- cytotoxic T-lymphocyte-associated protein 4 precursor
- CD152 protein
- cytotoxic T-lymphocyte protein 4
- cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM
- cytotoxic T-lymphocyte-associated protein 4
- costimulatory molecule B7 receptor
- cytotoxic T lymphocyte-associated antigen 4
- CD152 antigen
- cytotoxic T-lymphocyte-associated antigen 4
- CD152 isoform
- celiac disease 3
- cytotoxic T lymphocyte associated antigen 4 short spliced form
- cytotoxic T-lymphocyte antigen 4
- cytotoxic T-lymphocyte-associated serine esterase-4
- ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
- soluble form
- transmembrane form
- CTLA-4
- cytotoxic T lymphocyte-associated protein 4
- costimulatory molecule B7 receptor CD152
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- CTDNEP1B
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- CTD Nuclear Envelope Phosphatase 1 Regulatory Subunit 1
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