Deoxyribonuclease II, Lysosomal Protéines (DNASE2)

DNASE2 encodes a member of the DNase family. De plus, nous expédions Deoxyribonuclease II, Lysosomal Anticorps (53) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
DNASE2 13423 P56542
DNASE2 1777 O00115
DNASE2 171575 Q9QZK8
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Showing 9 out of 10 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$5,442.50
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$5,442.50
Détails
Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$205.80
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$405.71
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 10 to 12 Days
$785.40
Détails
Levure Rat His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,893.00
Détails
Levure Sanglier His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,929.67
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Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,938.83
Détails
Escherichia coli (E. coli) Humain T7 tag,His tag   100 μg Connectez-vous pour afficher 15 to 18 Days
$656.00
Détails

DNASE2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human , , ,
, , ,
Rat (Rattus)

Plus protéines pour Deoxyribonuclease II, Lysosomal (DNASE2) partenaires d'interaction

Fruit Fly (Drosophila melanogaster) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. These results confirm that DNase II and the ability to clear macromolecular DNA is essential for maintaining proper immune function in Drosophila.

  2. findings indicate that DNaseII can act cell autonomously to degrade DNA during nonapoptotic cell death.

Mouse (Murine) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. holocrine secretion is a DNase2-mediated form of programmed cell death and suggest that autophagy-dependent metabolism, DNA degradation

  2. Data show that Klf1 (Montrer KLF1 Protéines) is expressed in central macrophagse of erythroblastic islands and that it binds and activates the promoter of Dnase2a.

Human Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. Single nucleotide polymorphisms producing a loss-of-function variant of the enzymes in DNASE1 (Montrer DNASE1 Protéines), DNASE1L3 (Montrer DNASE1L3 Protéines), and DNASE2, possibly serving as a genetic risk factor for autoimmune diseases, were confirmed.

  2. 15 nonsynonymous human DNase II SNPs were genotyped in three ethnic groups including 16 different populations using the PCR-restriction fragment length polymorphism technique.

  3. study demonstrated the relationship of genotypes/haplotypes with the in vivo DNase II and promoter activities; significant correlations between genotype in each rheumatoid arthritis (RA)-related SNP and enzymatic activity levels were found; alleles associated with RA exhibited a reduction in serum DNase II activity.

  4. upregulation of expression during myelomonocytic differentiation of HL-60 and THP-1 cells

  5. Sp1 and Sp3 are involved in up-regulation of this enzyme's transcriptoin during cell differentiation of hl-60 cells.

  6. the enzyme is a monomeric phospholipase D-family member with a pseudodimeric protein fold

  7. The association of SNPs in the 5'-regulatory region of the DNA degrading enzyme DNASE2 with Rheumatoid Arthritis implies a role for this enzyme in the pathogenesis of this autoimmune disease.

Pig (Porcine) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. Proteolytic processing of porcine deoxyribonuclease II occurs in lysosomes but is not required for enzyme activation

  2. Data showed an association between PARP-1 and LEI/L-DNase II.

Profil protéine Deoxyribonuclease II, Lysosomal (DNASE2)

Profil protéine

This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

Gene names and symbols associated with DNASE2

  • Deoxyribonuclease II (DNaseII)
  • deoxyribonuclease II, lysosomal L homeolog (dnase2.L)
  • deoxyribonuclease 2, lysosomal (DNASE2)
  • deoxyribonuclease II, lysosomal (dnase2)
  • deoxyribonuclease II (dnase2)
  • deoxyribonuclease II alpha (Dnase2a)
  • deoxyribonuclease 2, lysosomal (Dnase2)
  • CG7780 Protéine
  • DDBDRAFT_0188966 Protéine
  • DDBDRAFT_0252883 Protéine
  • DDB_0188966 Protéine
  • DDB_0252883 Protéine
  • dDNase II Protéine
  • Dmel\\CG7780 Protéine
  • DNase Protéine
  • DNase-1 Protéine
  • DNase1 Protéine
  • DNase 1 Protéine
  • Dnase2 Protéine
  • Dnase2a Protéine
  • DNL Protéine
  • DNL2 Protéine
  • fa92d01 Protéine
  • LOC733868 Protéine
  • MGC80103 Protéine
  • wu:fa56d08 Protéine
  • wu:fa92d01 Protéine

Protein level used designations for DNASE2

deoxyribonuclease II , CG7780-PA , DNaseII-PA , acid DNase , deoxyribonuclease 1 , deoxyribonuclease II, lysosomal , deoxyribonuclease-2-alpha , fa56d08 , DNase II alpha , lysosomal DNase II , DNase II, lysosomal , R31240_2 , deoxyribonuclease II alpha

GENE ID SPECIES
48228 Drosophila melanogaster
446506 Xenopus laevis
476697 Canis lupus familiaris
733868 Xenopus (Silurana) tropicalis
747576 Pan troglodytes
100000399 Danio rerio
100171654 Pongo abelii
100599185 Nomascus leucogenys
8627734 Dictyostelium discoideum AX4
13423 Mus musculus
1777 Homo sapiens
171575 Rattus norvegicus
282218 Bos taurus
397398 Sus scrofa
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