anti-Dual Specificity Phosphatase 1 (DUSP1) Anticorps

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. De plus, nous expédions DUSP1 Kits (28) et DUSP1 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DUSP1 1843 P28562
DUSP1 19252 P28563
DUSP1 114856 Q64623
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Top anti-DUSP1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 111 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué IHC, ELISA, WB ABIN184638 (3.8µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. ABIN184638 (0.3µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 3 to 4 Days
349,82 €
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lymphoma tissue labeled with Anti-DUSP1/MKP-1 Polyclonal Antibody, Unconjugated (ABIN735368) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 9 to 12 Days
315,94 €
Détails
Humain Lapin Inconjugué IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using MKP1 (Phospho-Ser359) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué EIA, WB 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MKP1 (Ab-359) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MKP1 (Ab-359) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Alexa Fluor 488 IF (p)   100 μL Connectez-vous pour afficher 18 to 22 Days
426,22 €
Détails
Humain Chèvre Inconjugué EIA, IHC (p), WB 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Lapin Inconjugué IF, WB The anti-DUSP1 Pab (ABIN392905) is used in Western blot to detect DUSP1 in 293 cell lysate. 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Boeuf (Vache) Chèvre Inconjugué IHC (p), WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
357,50 €
Détails
Humain Chèvre Inconjugué IHC (p), IHC, ELISA, WB ABIN257653 staining (2µg/ml) of HeLa lysate (RIPA buffer, 35µg total protein per lane). Western Blot: MKP-1/DUSP1 Antibody [ABIN257653] - (0.3ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails

DUSP1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Mouse (Murine) ,
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anti-DUSP1 Anticorps mieux référencés

  1. Human Polyclonal DUSP1 Primary Antibody pour EIA, WB - ABIN360822 : Wu, Pew, Zou, Pang, Conzen: Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for 360822

  2. Human Polyclonal DUSP1 Primary Antibody pour IF (p), IHC (p) - ABIN735368 : Kato, Naiki-Ito, Naiki, Suzuki, Yamashita, Sato, Sagawa, Kato, Kuno, Takahashi: Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis. dans Oncotarget 2016 (PubMed)
    Show all 2 references for 735368

  3. Human Polyclonal DUSP1 Primary Antibody pour IF (p) - ABIN894519 : Khadir, Tiss, Abubaker, Abufarha, Al-Khairi, Cherian, John, Kavalakatt, Warsame, Al-Madhoun, Al-Ghimlas, Elkum, Behbehani, Dermime, Dehbi: MAP kinase phosphatase DUSP1 is overexpressed in human obese and modulated by physical activity. dans American journal of physiology. Endocrinology and metabolism 2014 (PubMed)

  4. Human Polyclonal DUSP1 Primary Antibody pour IHC (p), IHC - ABIN257653 : Alessi, Smythe, Keyse: The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. dans Oncogene 1993 (PubMed)

  5. Human Polyclonal DUSP1 Primary Antibody pour IHC, ELISA - ABIN1532716 : Keyse, Emslie: Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. dans Nature 1992 (PubMed)

Plus d’anticorps contre DUSP1 partenaires d’interaction

Human Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. Mean morning and evening DUSP1 mRNA levels showed significant increase during Ramadan compared to Shabaan, however, its diurnal rhythm was maintained. Morning IL-1alpha mRNA expression remained significantly higher than in the evening during Ramadan, but was markedly decreased compared to Shabaan.

  2. Methylation-mediated silencing of the DUSP-1 promoter does not appear to be associated with reduced expression, indicating the involvement of other factors in specific suppression of DUSP-1 in diabetes-associated cardiac hypertrophy.

  3. Increased MAP2K6 (Montrer MAP2K6 Anticorps), MAP4K3 (Montrer MAP4K3 Anticorps), and DUSP1 gene expressions in post-chemotherapy samples indicate a poor clinical outcome in osteosarcoma patients.

  4. The aim of this review is to shed light on the role of four different phosphatases (PTEN (Montrer PTEN Anticorps), PP2A (Montrer PPP2R4 Anticorps), CDC25 (Montrer RASGRF1 Anticorps) and DUSP1) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  5. Dual-specific phosphatase (DUSP1) was found to inhibit gallbladder cancer (GBC) cell proliferation, migration and invasion.

  6. The results presented here emphasize the importance of MKP-1 as a mediator of therapeutic effects of glucocorticoids in inflammatory lung diseases as well as its potential as a novel anti-inflammatory drug target.

  7. we show that IL-1 (Montrer IL1A Anticorps) induces robust p38a (Montrer MAPK14 Anticorps) activation both in the nucleus and in the cytoplasm/membrane.Following stimulation, p38a (Montrer MAPK14 Anticorps) activity returns to a basal level in absence of receptor degradation. While nuclear pulse is controlled by MKP1 through a negative feedback to pp38, its basal activity is controlled by both TAB1 (Montrer TAB1 Anticorps) and MKP1 through a positive feedback loop.

  8. Our results emphasize the importance of MKP-1 as a potential predictive biomarker for a subset of breast cancer patients with worse outcome and less susceptibility to treatment.

  9. Collectively, these data indicated that DUSP1 may induce the resistance against paclitaxel through the p38 MAPK (Montrer MAPK14 Anticorps)-mediated overexpression of p-glycoprotein in human ovarian cancer cells.

  10. silencing of IL1B (Montrer IL1B Anticorps) plus dexamethasone-induced DUSP1 significantly reduced IRF1 (Montrer IRF1 Anticorps) expression. IL1B (Montrer IL1B Anticorps)-induced expression of CXCL10 (Montrer CXCL10 Anticorps) was largely insensitive to dexamethasone, whereas other DUSP1-enhanced, IRF1 (Montrer IRF1 Anticorps)-dependent mRNAs showed various degrees of repression.

Mouse (Murine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. c-FOS and DUSP1 expression levels determine the threshold of tyrosine kinase (Montrer TYRO3 Anticorps) inhibitor (TKI) efficacy, such that growth-factor-induced expression of c-FOS and DUSP1 confers intrinsic resistance to TKI therapy in a wide-ranging set of leukemias.

  2. PTHrP (Montrer PTHLH Anticorps) counteracts the pro-apoptotic actions of reactive oxygen species by a mechanism dependent on MKP1-induced dephosphorylation.

  3. A2AR (Montrer ADORA2A Anticorps) signaling regulates both basal and LPS (Montrer TLR4 Anticorps)-induced DUSP1 levels in macrophages via activating the adenylate cyclase pathway.

  4. these data suggest an important role for DUSPs in regulating MAPK (Montrer MAPK1 Anticorps) dephosphorylation, with an emphasis on DUSP1, during early adipogenesis

  5. Loss of DUSP1 does not cause changes in cartilage degeneration and gait in a mouse model of spontaneous osteoarthritis at 21 months of age.

  6. Nr4a1 (Montrer NR4A1 Anticorps) induction is dependent on ERK1/2 (Montrer MAPK1/3 Anticorps) and that MKP-1 negatively regulates this induction.

  7. MKP-1 negatively regulates chemokine (Montrer CCL1 Anticorps)-driven osteoclast formation and subsequent bone resorption in response to LPS (Montrer TLR4 Anticorps) stimulation

  8. results suggest that the p38alpha (Montrer MAPK14 Anticorps)-MKP-1 signaling axis links IL-17R signaling in tissue-resident cells to autoimmune inflammation dependent on infiltrating T(H)17 cells.

  9. DUSP1 and tristetraprolin (Montrer ZFP36 Anticorps) cooperate to regulate macrophage responses to lipopolysaccharide.

  10. MKP-1 regulated the expression of MMP-12 (Montrer MMP12 Anticorps).

Cow (Bovine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. MKP-1 is the specific phosphatase induced by AngII and involved in the negative feedback mechanism ensuring adequate ERK1/2 (Montrer MAPK1/3 Anticorps)-mediated aldosterone production in response to the hormone.

Pig (Porcine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. Agonist stimulation of vascular smooth muscle increases PKC (Montrer FYN Anticorps) activity, which, in turn, increases MKP-1 activity and maintains MAPK1 (Montrer MAPK1 Anticorps) activity at submaximal values.

DUSP1 profil antigène

Profil protéine

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.

Gene names and symbols associated with DUSP1

  • dual specificity phosphatase 1 (DUSP1) anticorps
  • dual specificity phosphatase 1 (dusp1) anticorps
  • dual specificity phosphatase 1 (Dusp1) anticorps
  • 3CH134 anticorps
  • cb269 anticorps
  • CL100 anticorps
  • DUSP1 anticorps
  • erp anticorps
  • HVH1 anticorps
  • id:ibd2586 anticorps
  • mkp-1 anticorps
  • Mkp1 anticorps
  • PTPN10 anticorps
  • Ptpn16 anticorps
  • sb:cb269 anticorps
  • U19515 anticorps
  • wu:fd19g02 anticorps
  • wu:fe50g09 anticorps
  • zgc:55920 anticorps

Protein level used designations for DUSP1

dual specificity protein phosphatase 1 , dual specificity phosphatase 1 , mkp-1 , MAP kinase phosphatase 1 , dual specificity protein phosphatase hVH1 , mitogen-activated protein kinase phosphatase 1 , protein-tyrosine phosphatase CL100 , serine/threonine specific protein phosphatase , mitogen-activated protein kinase phosphatase-1 , protein tyrosine phosphatase, non-receptor type 16 , protein-tyrosine phosphatase 3CH134 , protein-tyrosine phosphatase ERP , 3CH134/CL100 PTPase , MAP kinase phosphatase-1 , mitogen-activated protein (MAP) kinase phosphatase-1 , oxidative stress-inducible protein tyrosine phosphatase , protein tyrosine phosphatase non-receptor type 16 , protein-tyrosine phosphatase non-receptor type 16 , MAPK phosphatase 1

GENE ID SPECIES
374192 Gallus gallus
471742 Pan troglodytes
100219518 Taeniopygia guttata
100340993 Oryctolagus cuniculus
406340 Danio rerio
1843 Homo sapiens
19252 Mus musculus
114856 Rattus norvegicus
489117 Canis lupus familiaris
539175 Bos taurus
100522469 Sus scrofa
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