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The protein encoded by GNPDA2 is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. De plus, nous expédions Glucosamine-6-Phosphate Deaminase 2 Protéines (6) et Glucosamine-6-Phosphate Deaminase 2 Kits (3) et beaucoup plus de produits pour cette protéine.
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GNPDA1 (Montrer GNPDA1 Anticorps) siRNA induced GFAT2 (Montrer GFPT2 Anticorps) which was hardly measurable in these cells under standard culture conditions, GNPDA2 siRNA increased GFAT1 (Montrer GFPT1 Anticorps), and GFAT1 (Montrer GFPT1 Anticorps) siRNA increased the expression of hyaluronan synthase 2 (HAS2 (Montrer HAS2 Anticorps)). Silencing of GFAT1 (Montrer GFPT1 Anticorps) stimulated GNPDA1 (Montrer GNPDA1 Anticorps) and GDPDA2, and inhibited cell migration.
Data show that SNPs in SEC16B (Montrer SEC16B Anticorps) and TMEM18 (Montrer TMM18 Anticorps) were significantly associated with obesity, and the SNPs in GNPDA2, BDNF (Montrer BDNF Anticorps), FAIM2 (Montrer FAIM2 Anticorps) and MC4R (Montrer MC4R Anticorps) were marginally associated with obesity in Japanese.
The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
glcN6P deaminase 2
, glucosamine-6-phosphate isomerase 2
, glucosamine-6-phosphate isomerase SB52
, GNPDA 2