Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) Kits ELISA

The protein encoded by MTHFD1L is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. De plus, nous expédions MTHFD1L Anticorps (35) et MTHFD1L Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
MTHFD1L 25902 Q6UB35
Anti-Rat MTHFD1L MTHFD1L 361472  
MTHFD1L 270685 Q3V3R1
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Catalogue No. Reactivité Sensibilité Gamme Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) 0.312-20 ng/mL 96 Tests Connectez-vous pour afficher 13 to 17 Days
945,85 €
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Humain
96 Tests Connectez-vous pour afficher 13 to 17 Days
788,70 €
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96 Tests Connectez-vous pour afficher 13 to 17 Days
945,85 €
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Plus Kits ELISA pour MTHFD1L partenaires d'interaction

Human Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) interaction partners

  1. Studies reported that the A allele of a polymorphism in a gene involved in folate metabolism, MTHFD1L, showed a genome-wide significant association with late-onset Alzheimer's Disease.

  2. rs6922269 variant at MTHFD1L gene could be an important prognostic factor for cardiovascular mortality in patients after ACS (Montrer PLA2G15 Kits ELISA).

  3. MTHFD1L rs6922269 genotype is associated with active vitamin B12 (Montrer NDUFB3 Kits ELISA) levels at baseline and may be a marker of prognostic risk in patients with established coronary heart disease.

  4. Results indicate that miR (Montrer MLXIP Kits ELISA)-9 and MiR (Montrer MLXIP Kits ELISA)-197 specifically downregulate MTHFD1L in HEK293 and MCF-7 cells and that SNPrs7646 affects miR (Montrer MLXIP Kits ELISA)-197 binding to the MTHFD1L 3' UTR (Montrer UTS2R Kits ELISA) causing gene repression in the presence of the allele associated with neural tube defects.

  5. The rs3832406 polymorphism was associated with isolated cleft lip with or without cleft palate.(MTHFD1L)

  6. This study support a role of MTHFD1L gene in late-onset Alzheimer's disease in a Northern Han Chinese population.

  7. No evidence of association between the MTHFD1L marker and susceptibility to Alzheimer's disease is found in a sample from a Spanish population.

  8. Prevalence of minor allele A (adenosine) in rs11754661 single nucleotide polymorphism of MTHFD1L contributes to the risk of Alzheimer's disease in a Han population of mainland China.

  9. mitochondrial C1-tetrahydrofolate synthase (Montrer MTHFD1 Kits ELISA) gene structure and tissue distribution

  10. Two of the three alleles of rs3832406 are functionally different and influence the splicing efficiency of the alternate MTHFD1L mRNA transcripts.

Mouse (Murine) Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) interaction partners

  1. Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice.

  2. Data show that the MTHFD1L enzyme is present in mitochondria from normal embryonic tissues and embryonic fibroblast cell lines, and embryonic mitochondria possess the ability to synthesize formate from glycine.

MTHFD1L profil antigène

Antigen Summary

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MTHFD1L

  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L) anticorps
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (Mthfd1l) anticorps
  • 2410004L15Rik anticorps
  • AI647056 anticorps
  • dJ292B18.2 anticorps
  • Fthfsdc1 anticorps
  • MTC1THFS anticorps

Protein level used designations for MTHFD1L

10-formyl-THF synthetase , formyltetrahydrofolate synthetase domain containing 1 , monofunctional C1-tetrahydrofolate synthase, mitochondrial , formyltetrahydrofolate synthetase

GENE ID SPECIES
25902 Homo sapiens
361472 Rattus norvegicus
476245 Canis lupus familiaris
534296 Bos taurus
270685 Mus musculus
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