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Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA. De plus, nous expédions PLAGL2 Protéines (3) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal PLAGL2 Primary Antibody pour EIA, IF - ABIN1449972
Kas, Voz, Hensen, Meyen, Van de Ven: Transcriptional activation capacity of the novel PLAG family of zinc finger proteins. dans The Journal of biological chemistry 1998
Our findings indicated that PLAGL2 might be a very upstream key molecule regulating Epithelial-mesenchymal transition involved in Wnt (Montrer WNT2 Anticorps)/bcatenin signaling pathway in Colorectal adenocarcinoma
PLAGL2 expression induces lamellipodia formation and disruption of stress fiber formation.
PLAGL2 regulate cell cycle and apoptosis via activation of the p53 (Montrer TP53 Anticorps) family member, p73 (Montrer TP73 Anticorps), in human promonocytic U937 cells.
Transcriptome analysis revealed that these differentiation-suppressive activities are attributable in part to PLAGL2 modulation of Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling
The data identify PC2 (Montrer KRT6B Anticorps) as a novel PLAGL2-binding protein and important mediator of PLAGL2 transactivation.
PLAGL2 may modulate SP-C (Montrer SFTPC Anticorps) expression during lung development.
Plag1 (Montrer PLAG1 Anticorps) and Plagl2 are novel leukemia oncogenes that act by expanding hematopoietic progenitors expressing CbF beta (Montrer CBFB Anticorps)-SMMHC (Montrer MYH11 Anticorps).
These data clearly identify PLAGL2 as a novel regulator of NCF2/p67phox (Montrer NCF2 Anticorps) gene expression as well as NADPH oxidase (Montrer NOX1 Anticorps) activity and contribute to a greater understanding of the transcriptional regulation of NCF2 (Montrer NCF2 Anticorps).
Coexpression of Tip60 (Montrer KAT5 Anticorps) and PLAGL2 completely abolishes the sumoylation of PLAGL2.
Nuclear PLAGL2 occupied and transactivated the endogenous SP-C (Montrer SFTPC Anticorps) promoter in hypoxic lung cells.These results further suggest that PLAGL2 is an oxidative stress responding regulator in lung cells.
induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis.
PlagL2 regulates important aspects of dietary lipid absorption, and the PlagL2(-/-) animal model has implications for the amelioration of obesity and the metabolic syndrome.
Increased cell injury and/or death could be caused directly by the upregulation of bNip3 (Montrer BNIP3 Anticorps), a preapoptotic molecule that dimerizes with Bcl-2 (Montrer BCL2 Anticorps), or indirectly by the aberrant expression of SP-C (Montrer SFTPC Anticorps)-induced endoplasmic reticulum stress in epithelial cells.
Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA.
zinc finger protein PLAGL2
, pleiomorphic adenoma gene-like 2
, zinc finger protein PLAGL2-like
, C2H2-type zinc finger protein
, pleiomorphic adenoma-like protein 2
, pleomorphic adenoma gene like 2