anti-Ring Finger Protein 139 (RNF139) Anticorps

The protein encoded by RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. De plus, nous expédions Ring Finger Protein 139 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
RNF139 11236 Q8WU17
RNF139 75841 Q7TMV1
RNF139 315000  
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Top anti-Ring Finger Protein 139 Anticorps sur anticorps-enligne.fr

Showing 10 out of 57 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-RNF139 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué WB RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 on formalin-fixed paraffin-embedded human tonsil (antibody concentration 3 µg/mL). 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$676.50
Détails
Chien Chèvre Inconjugué EIA, IHC (p), WB   0.1 mg Connectez-vous pour afficher 12 to 15 Days
$375.38
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to RNF139 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 . 100 μg Connectez-vous pour afficher 11 to 12 Days
$430.00
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Connectez-vous pour afficher 11 to 12 Days
$298.57
Détails
Humain Chèvre Inconjugué IHC, ELISA, WB (1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$326.89
Détails
Humain Chèvre Inconjugué IHC (p), ELISA, WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$451.00
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$433.13
Détails
Humain Souris Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$537.17
Détails

RNF139 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Ring Finger Protein 139 Anticorps mieux référencés

  1. Human Polyclonal RNF139 Primary Antibody pour ELISA, WB - ABIN564886 : Brauweiler, Lorick, Lee, Tsai, Chan, Weissman, Drabkin, Gemmill: RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene. dans Oncogene 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal RNF139 Primary Antibody pour IHC (p), ELISA - ABIN564887 : Adams, Simms, Abdelhamed, Dawe, Szymanska, Logan, Wheway, Pitt, Gull, Knowles, Blair, Cross, Sayer, Johnson: A meckelin-filamin A interaction mediates ciliogenesis. dans Human molecular genetics 2012 (PubMed)

Plus d’anticorps contre Ring Finger Protein 139 partenaires d’interaction

Human Ring Finger Protein 139 (RNF139) interaction partners

  1. interaction with Bag1 (Montrer BAG1 Anticorps) then shifts hERG (Montrer KCNH2 Anticorps) degradation to the membrane-anchored E3 ligase TRC8 and its E2-conjugating enzyme Ube2g2 (Montrer UBE2G2 Anticorps), as determined by siRNA screening

  2. TRC8 and TMEM129 are endoplasmic reticulum-associated degradation ubiquitin E3 ligases for viral and cellular targeting of MHC class I. (Review)

  3. TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 (Montrer HMOX1 Anticorps) for ubiquitination and degradation.

  4. TRC8 function may provide a regulatory link between the lipid and protein biosynthetic pathways.

  5. TRC8 modulation of sterol response element binding protein activity comprises a novel regulatory link between growth control and the cholesterol/lipid homeostasis pathway.

  6. The presence of diploid and tetraploid tumor cells with and without TRC8 deletions on the nontranslocated chromosome suggest that loss of the remaining normal allele of TRC8 may contribute to tumor development at later stages.

  7. TRC8 is a novel sterol-sensing endoplasmic reticulum membrane protein (Montrer SLC39A6 Anticorps) that hinders SREBP-2 (Montrer SREBF2 Anticorps) processing through interaction with SREBP-2 (Montrer SREBF2 Anticorps) and SCAP (Montrer SH2D2A Anticorps), regulating its own turnover rate by means of its E3 ubiquitin ligase (Montrer MUL1 Anticorps) activity

  8. Data show that the TRC8 E3 ligase is required for MHC I dislocation from the ER and identify a new complex associated with mammalian ERAD.

Ring Finger Protein 139 (RNF139) profil antigène

Profil protéine

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Gene names and symbols associated with RNF139

  • ring finger protein 139 (RNF139) anticorps
  • ring finger protein 139 (Rnf139) anticorps
  • ring finger protein 139 (rnf139) anticorps
  • ring finger protein 139 S homeolog (rnf139.S) anticorps
  • 4930555P18Rik anticorps
  • HRCA1 anticorps
  • RCA1 anticorps
  • rnf139 anticorps
  • TRC8 anticorps
  • zgc:175173 anticorps

Protein level used designations for RNF139

E3 ubiquitin-protein ligase RNF139 , multiple membrane spanning receptor TRC8 , patched related protein translocated in renal cancer , translocation in renal carcinoma on chromosome 8 protein , RING finger protein 139 , ring finger protein 139 S homeolog

GENE ID SPECIES
11236 Homo sapiens
75841 Mus musculus
315000 Rattus norvegicus
420338 Gallus gallus
609422 Canis lupus familiaris
100067392 Equus caballus
100156613 Sus scrofa
788471 Bos taurus
100447707 Pongo abelii
100734055 Cavia porcellus
100357210 Oryctolagus cuniculus
100144552 Danio rerio
444792 Xenopus laevis
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