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SMAD, Mothers Against DPP Homolog 5 (SMAD5) Kits ELISA

The protein encoded by SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. De plus, nous expédions SMAD5 Anticorps (105) et SMAD5 Protéines (14) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
SMAD5 4090 Q99717
SMAD5 17129 P97454
SMAD5 59328 Q9R1V3
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Plus Kits ELISA pour SMAD5 partenaires d'interaction

Zebrafish SMAD, Mothers Against DPP Homolog 5 (SMAD5) interaction partners

  1. TGFbeta1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway.

  2. Alk3 and Alk3b, as well as SMAD5, are essential cellular mediators of BMP signaling in zebrfish.

  3. Data show that interplay of Smad1 (Montrer SMAD1 Kits ELISA)/5 and MAP kinase (Montrer MAPK1 Kits ELISA) signaling system (ERK (Montrer MAPK1 Kits ELISA) signalling) is essential for haemogenic endothelium-based haematopoietic stem cell emergence.

  4. this study uncovers that smad1 (Montrer SMAD1 Kits ELISA) and smad9 (Montrer SMAD9 Kits ELISA) act redundantly to each other downstream of smad5 to mediate ventral specification and to regulate embryonic myelopoiesis.

  5. Functional investigation of a subset of these genes, fgf10a (Montrer FGF10 Kits ELISA), tgfb2 (Montrer TGFB2 Kits ELISA), pax9 (Montrer PAX9 Kits ELISA), and smad5 revealed their necessity in zebrafish palatogenesis.

  6. maternally supplied Smad5 is already required to mediate ventral specification prior to zygotic Bmp2 (Montrer BMP4 Kits ELISA)/7 signaling to establish the initial dorsoventral asymmetry

  7. Data show that patterning of the eye primordia in Smad5-deficient embryos starts during blastula and early gastrula stages.

  8. that specificity of BMP signaling output, with respect to hematopoiesis, can be explained by differential functions of Smad1 (Montrer SMAD1 Kits ELISA) and Smad5.

  9. Data show that Smad5 expression is ubiquitous during testis development but becomes cell-specific in the adult.

Human SMAD, Mothers Against DPP Homolog 5 (SMAD5) interaction partners

  1. the BMP-2 (Montrer BMP2 Kits ELISA)/Smad1 (Montrer GARS Kits ELISA)/5/RUNX2 (Montrer RUNX2 Kits ELISA) signaling pathway participates in the silicon-mediated induction of COL-1 and osteocalcin (Montrer BGLAP Kits ELISA) synth

  2. miR (Montrer MLXIP Kits ELISA)-23a and miR (Montrer MLXIP Kits ELISA)-27a target SMAD5 and regulate apoptosis in human granulosa cells via the FasL (Montrer FASL Kits ELISA)-Fas (Montrer FAS Kits ELISA) pathway

  3. Our findings suggest that suppression of miR (Montrer MLXIP Kits ELISA)-222-3p activity promoted osteogenic differentiation hBMSCs through regulating Smad5-RUNX2 (Montrer RUNX2 Kits ELISA) signaling axis.

  4. Overexpression of the BMP4 (Montrer BMP4 Kits ELISA)/SMAD4 (Montrer SMAD4 Kits ELISA)/SMAD5 signaling pathway could predict poor clinical outcome in skull base chordomas, suggesting activation of this pathway is involved in chordoma pathogenesis.

  5. The polycomb group protein L3MBTL1 (Montrer L3MBTL1 Kits ELISA) represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells.

  6. adult human Sertoli cells assumed similar morphological features, stable global gene expression profiles and numerous proteins, and activation of AKT (Montrer AKT1 Kits ELISA) and SMAD1 (Montrer GARS Kits ELISA)/5 during long-period culture.

  7. balance between Smad1 (Montrer GARS Kits ELISA)/5- and Smad2 (Montrer SMAD2 Kits ELISA)/3-dependent signaling defines the outcome of the effect of TGF-beta (Montrer TGFB1 Kits ELISA) on atherosclerosis where Smad1 (Montrer GARS Kits ELISA)/5 is responsible for proatherogenic effects

  8. among the 15 SNPs, rs3206634 was significantly associated with KD in a recessive model (odds ratio = 2.31, p = 0.019), whereas there was no association between any of the 15 SNPs and CALs (Montrer CA8 Kits ELISA).

  9. Our results indicated that KGN promoted the type-I collagen synthesis of dermal fibroblasts in vitro and in the dermis of mice through activation of the smad4 (Montrer SMAD4 Kits ELISA)/smad5 pathway.

  10. Inhibiting Smurf1 (Montrer SMURF1 Kits ELISA) mediated ubiquitination of Smad1 (Montrer GARS Kits ELISA)/5.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 5 (SMAD5) interaction partners

  1. BetA can enhance in vivo osteogenic potentials of BMP2 (Montrer BMP2 Kits ELISA), possibly via stimulating Smad 1 (Montrer SMAD1 Kits ELISA)/5/8 and p38 (Montrer CRK Kits ELISA) pathways, and combination of both agents can be considered as a therapeutic strategy for bone diseases.

  2. Data show that in R-Smad (Montrer SMAD1 Kits ELISA) proteins Smad1 (Montrer SMAD1 Kits ELISA);Smad5 knockout embryonic stem cells (mESCs), the bone morphogenetic proteins (BMP)-SMAD (Montrer SMAD1 Kits ELISA) signaling is dispensable for self-renewal.

  3. Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).

  4. The crystal structure of Smad5-MH1 (Montrer SCN5A Kits ELISA) domain in complex with a composite DNA sequence demonstrates that the MH1 (Montrer SCN5A Kits ELISA) domain is targeted to a binding site with modular binding modes, and the length of the DNA spacer affects the MH1 (Montrer SCN5A Kits ELISA) assembly.

  5. The findings demonstrate for the first time that KMUP-1 can promote osteoblast maturation and differentiation in vitro via BMP-2 (Montrer BMP2 Kits ELISA)/Smad1 (Montrer SMAD1 Kits ELISA)/5/8 and Wnt (Montrer WNT2 Kits ELISA)/beta-catenin (Montrer CTNNB1 Kits ELISA) pathways.

  6. FLI1 (Montrer FLI1 Kits ELISA) and GATA2 (Montrer GATA2 Kits ELISA) are upstream regulators of SMAD1 (Montrer SMAD1 Kits ELISA) and SMAD5 expression in endothelial cells.

  7. Data indicate that PDGF (Montrer PDGFA Kits ELISA)-AA promotes mesenchymal stem cel migration via bone morphogenetic protein 2 (BMP2 (Montrer BMP2 Kits ELISA))-smad (Montrer SMAD1 Kits ELISA) proteins smad1 (Montrer SMAD1 Kits ELISA)/5/8 activation requires lysosome-mediated degradation of PDGF (Montrer PDGFA Kits ELISA) alpha Receptor (PDGFRalpha).

  8. some pSMAD1/5 targets, like Gata3 (Montrer GATA3 Kits ELISA), function specifically in transit amplifying cell lineage-progression.

  9. The effects of a soy-free diet on the risk of granulosa cell tumors in mice with conditional double knockout of Smad1 (Montrer SMAD1 Kits ELISA) and Smad5 are reported.

  10. our data suggest a pivotal role for canonical BMP signaling demonstrating distinguished nonoverlapping function of pSmad8 with pSmad1 and pSmad5 in hfSCs regulation and hair morphogenesis but a redundant role in adult hair progenitors differentiation.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 5 (SMAD5) interaction partners

  1. a detailed computational model for TGF-beta (Montrer TGFB1 Kits ELISA) signalling that incorporates elements of previous models together with crosstalking between Smad1 (Montrer SMAD1 Kits ELISA)/5/8 and Smad2 (Montrer SMAD2 Kits ELISA)/3 channels through a negative feedback loop dependent on Smad7 (Montrer SMAD7 Kits ELISA).

SMAD5 profil antigène

Antigen Summary

The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with SMAD5

  • SMAD family member 5 (SMAD5) anticorps
  • MAD homolog 5 (Drosophila) (smad5) anticorps
  • SMAD family member 4, gene 2 (smad4.2-b) anticorps
  • SMAD family member 5 (Smad5) anticorps
  • 1110051M15Rik anticorps
  • AI451355 anticorps
  • DKFZp468M0619 anticorps
  • dpc4 anticorps
  • Dwf-C anticorps
  • DWFC anticorps
  • fb67b04 anticorps
  • jip anticorps
  • JV5-1 anticorps
  • mad anticorps
  • madh4 anticorps
  • Madh5 anticorps
  • MusMLP anticorps
  • sb:cb400 anticorps
  • SBN anticorps
  • SMAD5 anticorps
  • smad10 anticorps
  • smd5 anticorps
  • wu:fb67b04 anticorps
  • xsmad4 anticorps
  • XSmad4alpha anticorps

Protein level used designations for SMAD5

mothers against decapentaplegic homolog 5 , SMA- and MAD-related protein 5 , SMAD 5 , SMAD family member 5 , mothers against DPP homolog 5 , pgy , piggytail , somitabun , MAD, mothers against decapentaplegic homolog 5 , SMAD, mothers against DPP homolog 5 , mothers against decapentaplegic, drosophila, homolog of, 5 , MAD homolog 5 , Smad 5 , dwarfin-C , mSmad5 , Mothers against decapentaplegic homolog 5

GENE ID SPECIES
100033851 Equus caballus
30641 Danio rerio
403398 Xenopus laevis
4090 Homo sapiens
17129 Mus musculus
59328 Rattus norvegicus
395679 Gallus gallus
481520 Canis lupus familiaris
768050 Bos taurus
100173534 Pongo abelii
100303615 Sus scrofa
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