anti-UPF3 Regulator of Nonsense Transcripts Homolog B (Yeast) (UPF3B) Anticorps

UPF3B encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. De plus, nous expédions UPF3B Protéines (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
UPF3B 65109 Q9BZI7
UPF3B 68134  
UPF3B 313449  
Comment commander chez anticorps-enligne
  • +33 (0)1 76 63 32 65
  • +33 (0)1 74 18 08 22
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-UPF3B Anticorps sur anticorps-enligne.fr

Showing 10 out of 22 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB <b>WB Suggested Anti-UPF3B Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Humain Lapin Inconjugué IHC (p), WB Anti- UPF3B/RENT3B Picoband antibody, IHC(P) IHC(P): Rat Testis Tissue 100 μg Connectez-vous pour afficher 8 to 11 Days
340,48 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC (p), WB 100 μg Connectez-vous pour afficher 11 to 14 Days
583,17 €
Détails
Chien Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails
Chien Lapin Inconjugué IHC, ELISA, WB 100 μg Connectez-vous pour afficher 6 to 8 Days
374,52 €
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 6 to 8 Days
459,65 €
Détails
Humain Lapin Inconjugué ICC, IF, WB Immunocytochemistry/Immunofluorescence: UPF3B Antibody  - Staining of human cell line SiHa shows localization to nucleus, nucleoli & cytosol. Western Blot: UPF3B Antibody  - Western blot analysis in human cell line RT-4. 100 μL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails
Humain Lapin Inconjugué IHC, WB UPF3B antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain EpitheliaI cells of fundic gland (arrows) in Human Stomach. Magnification is at 400X UPF3B antibody used at 1.25 ug/ml to detect target protein. 100 μg Connectez-vous pour afficher 6 to 8 Days
379,93 €
Détails
Humain Lapin Inconjugué WB Western Blot: UPF3B Antibody [NBP1-57233] - Titration: 0.2-1 ug/ml, Positive Control: Human heart. 100 μL Connectez-vous pour afficher 4 to 7 Days
426,25 €
Détails

UPF3B Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Human


Mouse (Murine)


Rat (Rattus)


anti-UPF3B Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal UPF3B Primary Antibody pour IHC, WB - ABIN2776563 : Lehner, Sanderson: A protein interaction framework for human mRNA degradation. dans Genome research 2004 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre UPF3B partenaires d’interaction

Human UPF3 Regulator of Nonsense Transcripts Homolog B (Yeast) (UPF3B) interaction partners

  1. The authors discovered that UPF3B (i) interacts with the release factors, (ii) delays translation termination and (iii) dissociates post-termination ribosomal complexes that are devoid of the nascent peptide.

  2. UPF3B gene mutation is associated with Lujan-Fryns syndrome.

  3. the neurodevelopmental phenotype of UPF3B missense mutation is caused by impairment of nonsense-mediated mRNA decay pathway function altering neuronal differentiation.

  4. These findings indicate that SATB2 (Montrer SATB2 Anticorps) activates UPF3B expression through binding to its promoter.

  5. Data indicate the mutation p.R430X of UPF3B gene as the genetic etiology in the mental retardation pedigree.

  6. results demonstrate that the UPF3B-dependent NMD pathway is a major regulator of the transcriptome and that its targets have important roles in neuronal cells.

  7. The two cases with renal dysplasia and developmental delay showed remarkable clinical variability despite having the same mutation in UPF3B.

  8. Our results demonstrate that in addition to Lujan-Fryns and FG syndromes, UPF3B protein truncation mutations can cause also nonspecific XLMR (Montrer DLG3 Anticorps).

  9. 3.4 A resolution crystal structure of a minimal UPF3b-EJC assembly, consisting of the interacting domains of five proteins (UPF3b, MAGO (Montrer MAGOHB Anticorps), Y14 (Montrer RBM8A Anticorps), eIF4AIII (Montrer EIF4A3 Anticorps), and Barentsz (Montrer CASC3 Anticorps)) together with RNA and adenylyl-imidodiphosphate

  10. A conserved domain of hUpf3b mediates an interaction with the EJC protein Y14 (Montrer RBM8A Anticorps). Y14 (Montrer RBM8A Anticorps) is required for nonsense-mediated decay induced by tethered hUpf3b.

Mouse (Murine) UPF3 Regulator of Nonsense Transcripts Homolog B (Yeast) (UPF3B) interaction partners

  1. Analysis revealed that UPF3A (Montrer UPF3A Anticorps) is a broadly acting nonsense-mediated RNA decay inhibitor. This discovery implies that UPF3A (Montrer UPF3A Anticorps) and UPF3B do not primarily work in a complementary or redundant manner as previously supposed; instead, they oppose each other, allowing this paralog pair to serve as a molecular rheostat to modulate the level of gene expression during development.

  2. Evidence suggests Upf3b-dependent nonsense-mediated mRNA decay is regulated at multiple levels during development including regulation of expression and sub-cellular localization of Upf3b.

UPF3B profil antigène

Profil protéine

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with UPF3B

  • UPF3 regulator of nonsense transcripts homolog B (yeast) (UPF3B) anticorps
  • UPF3 regulator of nonsense transcripts homolog B (yeast) (Upf3b) anticorps
  • 5730594O13Rik anticorps
  • AI317193 anticorps
  • AW541158 anticorps
  • HUPF3B anticorps
  • MRXS14 anticorps
  • RENT3B anticorps
  • RGD1560264 anticorps
  • UPF3X anticorps

Protein level used designations for UPF3B

hUpf3p-X , nonsense mRNA reducing factor 3B , regulator of nonsense transcripts 3B , up-frameshift suppressor 3 homolog B , up-frameshift suppressor 3 homolog on chromosome X , hUPF3B

GENE ID SPECIES
65109 Homo sapiens
481031 Canis lupus familiaris
616181 Bos taurus
68134 Mus musculus
313449 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-UPF3B (UPF3B) Anticorps
Avez-vous cherché autre chose?