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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. De plus, nous expédions UBE2E3 Protéines (9) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal UBE2E3 Primary Antibody pour EIA, IHC (p) - ABIN357598
Ito, Kato, Matsuda, Kimura, Okano: cDNA cloning, characterization, and chromosome mapping of UBE2E3 (alias UbcH9), encoding an N-terminally extended human ubiquitin-conjugating enzyme. dans Cytogenetics and cell genetics 1999
Data indicate that ubiquitin-conjugating enzyme (Montrer Ube2t Anticorps) UBE2E3 and importin 11 (Montrer IPO11 Anticorps) (Imp (Montrer IMPA1 Anticorps)-11)promote the nuclear accumulation and activity of transcription factor NF-E2 (Montrer NFE2 Anticorps) (Nrf2 (Montrer GABPA Anticorps)) by restricting the transcription factor from partitioning to the mitochondria.
UBE2E3 is essential for the proliferation of RPE-1 (Montrer PMEL Anticorps) cells and is downregulated during RPE (Montrer RPE Anticorps) layer maturation in the developing mouse eye.
UBC4 (Montrer UBE2D2 Anticorps)-testis isoform plays a role in early maturation of the testis
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
ubiquitin-conjugating enzyme E2 E3
, ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
, Ubiquitin-conjugating enzyme E2 E3
, putative ubiquitin-conjugating enzyme family
, ubiquitin-conjugating enzyme E2E 3
, ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog)
, ubiquitin carrier protein E3
, ubiquitin-conjugating enzyme E2-23 kDa
, ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5)
, ubiquitin-protein ligase E3
, ubiquitin-conjugating enzyme 4
, ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog