rho Guanine Nucleotide Exchange Factor (GEF) 10 Protéines (ARHGEF10)

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. De plus, nous expédions ARHGEF10 Anticorps (33) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
ARHGEF10 9639 O15013
ARHGEF10 234094 Q8C033
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Showing 3 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$12,127.90
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$12,127.90
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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ARHGEF10 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour rho Guanine Nucleotide Exchange Factor (GEF) 10 (ARHGEF10) partenaires d'interaction

Human rho Guanine Nucleotide Exchange Factor (GEF) 10 (ARHGEF10) interaction partners

  1. Ectopic expression of an N-terminal-truncated ARHGEF10 mutant led to the generation of large vesicle-like structures containing both Rab6 (Montrer RAB6A Protéines) and Rab8 (Montrer RAB8A Protéines).

  2. This study provided new insights into the roles of ARHGEF10 SNPs rs2280887, rs9657362, and rs4480162 in the development and progression of ischemic stroke in northern Chinese Han population.

  3. A significant association of ARHGEF10 with paclitaxel chemotherapy induced peripheral neuropathy was found.

  4. Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10).

  5. the rs4376531 polymorphism in the ARHGEF10 gene is a risk factor for atherothrombotic stroke in the Han Chinese population

  6. The functional single-nucleotide polymorphism of ARHGEF10 confers the susceptibility to atherothrombotic stroke.

  7. data support a role for ARHGEF10 in developmental myelination of peripheral nerves

  8. Gef10 is the third member of a Rho-specific GEF (Montrer SLC2A4RG Protéines) family with unusual protein architecture

  9. A novel RhoA (Montrer RHOA Protéines)-dependent signaling pathway under the control of ARHGEF10 has a pivotal role in the regulation of the cell division cycle.

Profil protéine ARHGEF10

Profil protéine

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals.

Gene names and symbols associated with ARHGEF10

  • Rho guanine nucleotide exchange factor 10 (ARHGEF10)
  • Rho guanine nucleotide exchange factor 10 (arhgef10)
  • Rho guanine nucleotide exchange factor (GEF) 10 (arhgef10)
  • Rho guanine nucleotide exchange factor (GEF) 10 (Arhgef10)
  • 6430549H08Rik Protéine
  • ARHGEF10 Protéine
  • GEF10 Protéine
  • mKIAA0294 Protéine
  • wu:fi38h08 Protéine

Protein level used designations for ARHGEF10

Rho guanine nucleotide exchange factor (GEF) 10 , rho guanine nucleotide exchange factor 10-like , Rho guanine nucleotide exchange factor 10 , rho guanine nucleotide exchange factor 10

GENE ID SPECIES
100138303 Bos taurus
100230702 Taeniopygia guttata
100490713 Xenopus (Silurana) tropicalis
334278 Danio rerio
421900 Gallus gallus
609511 Canis lupus familiaris
9639 Homo sapiens
234094 Mus musculus
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