CDH6 anticorps (Extracellular Domain)
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- Antigène Voir toutes CDH6 Anticorps
- CDH6 (K-Cadherin (CDH6))
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Épitope
- Extracellular Domain
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CDH6 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Clone 2B6 recognizes the extracellular domain of Cadherin-6.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Rat.
- Purification
- Purified
- Immunogène
- Affinity purified extracellular domain of human cadherin-6-GST fusion protein
- Clone
- 2B6
- Isotype
- IgG1
- Top Product
- Discover our top product CDH6 Anticorps primaire
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- Indications d'application
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Immunoblotting (1: 25 - 1: 250). Immunocytochemistry. Immunohistochemistry on frozen sections when using a PBS buffer containing 0.1 mMCaCl2 and 0.1 mM MgCl2. Recommended range is 1: 25 - 1: 50 for immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CDH6 (K-Cadherin (CDH6))
- Autre désignation
- Cadherin-6 (CDH6 Produits)
- Synonymes
- anticorps KCAD, anticorps K-cadherin, anticorps cad6, anticorps cadherin-6, anticorps CAD6, anticorps c-cad6B, anticorps cadherin 6, anticorps Cdh6, anticorps CDH6
- Sujet
- Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. The cadherins generally contain five extracellular repeats, a transmembrane domain and a cytoplasmic tail that binds to the catenin family of cytoskeletal anchoring proteins which also function as signal transducers. The extracellular domains are responsible for the specificity of homophilic interactions between cells expressing the same cadherin. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4). Kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.Synonyms: CDH6, Cadherin K, K-Cadherin, Kidney cadherin
- ID gène
- 1004
- NCBI Accession
- NP_004923
- UniProt
- P55285
- Pathways
- Cell-Cell Junction Organization
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