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CYBA anticorps (PE)

CYBA Reactivité: Humain, Singe FACS Hôte: Souris Monoclonal 7D5 PE
N° du produit ABIN1449195
  • Antigène Voir toutes CYBA Anticorps
    CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
    Reactivité
    • 44
    • 19
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Singe
    Hôte
    • 40
    • 4
    Souris
    Clonalité
    • 40
    • 4
    Monoclonal
    Conjugué
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CYBA est conjugé à/à la PE
    Application
    • 35
    • 21
    • 17
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody recognizes the extracellular peptide portion of primate gp91phox of the Flavocytochrome b558.
    Aucune reactivité croisée
    Souris
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Monkey.
    Purification
    Protein A agarose
    Immunogène
    Human cytochrome b-rich fraction
    Clone
    7D5
    Isotype
    IgG1
    Top Product
    Discover our top product CYBA Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS, 0.09 % NaN3, 1 % BSA
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8 °C.
  • Antigène
    CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
    Autre désignation
    Cytochrome B-245 Light Chain (CYBA Produits)
    Synonymes
    anticorps zgc:66077, anticorps MGC80750, anticorps CYBA, anticorps p22-phox, anticorps p22phox, anticorps p22-PHOX, anticorps b558, anticorps nmf333, anticorps P22-PHOX, anticorps cytochrome b-245, alpha polypeptide, anticorps cytochrome b-245 alpha polypeptide L homeolog, anticorps cytochrome b-245 alpha polypeptide, anticorps cytochrome b-245 light chain-like, anticorps cytochrome b-245 alpha chain, anticorps p22-phox, anticorps cyba, anticorps cyba.L, anticorps CYBA, anticorps LOC101328418, anticorps Cyba
    Sujet
    The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome b558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
    ID gène
    1535
    NCBI Accession
    NP_000092
    UniProt
    P13498
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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