TOX anticorps (N-Term)
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- Antigène Voir toutes TOX Anticorps
- TOX (Thymus High Mobility Group Box Protein (TOX))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TOX est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- A 17 amino acid synthetic peptide near the amino terminus of Human TOX
- Isotype
- IgG
- Top Product
- Discover our top product TOX Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- TOX (Thymus High Mobility Group Box Protein (TOX))
- Autre désignation
- TOX (TOX Produits)
- Synonymes
- anticorps TOX1, anticorps 1700007F02Rik, anticorps thymocyte selection associated high mobility group box, anticorps thymocyte selection-associated high mobility group box, anticorps TOX, anticorps Tox
- Sujet
- TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development (1,2). It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.Synonyms: KIAA0808, Thymocyte selection-associated high mobility group box protein TOX, Thymus high mobility group box protein TOX
- Poids moléculaire
- 58 kDa
- ID gène
- 9760
- NCBI Accession
- NP_055544
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