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FNBP1 anticorps (AA 331-430) (HRP)

FNBP1 Reactivité: Poisson-ballons, Xenopus laevis WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712049
  • Antigène Voir toutes FNBP1 Anticorps
    FNBP1 (Formin Binding Protein 1 (FNBP1))
    Épitope
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 331-430
    Reactivité
    • 14
    • 14
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Poisson-ballons, Xenopus laevis
    Hôte
    • 23
    • 1
    • 1
    Lapin
    Clonalité
    • 24
    • 1
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FNBP1 est conjugé à/à la HRP
    Application
    • 24
    • 13
    • 13
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Poisson-ballons, Xenopus laevis
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Zebrafish
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FBP17
    Isotype
    IgG
    Top Product
    Discover our top product FNBP1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FNBP1 (Formin Binding Protein 1 (FNBP1))
    Autre désignation
    FBP17 (FNBP1 Produits)
    Synonymes
    anticorps MGC122623, anticorps MGC146466, anticorps FBP17, anticorps 1110057E06Rik, anticorps 2210010H06Rik, anticorps FBP1, anticorps Fbp17, anticorps formin binding protein 1, anticorps formin binding protein 1 L homeolog, anticorps FNBP1, anticorps fnbp1, anticorps Fnbp1, anticorps fnbp1.L
    Sujet

    Synonyms: FBP1, FBP17, FNBP1, FNBP1_HUMAN, Formin binding protein 1, Formin binding protein 17, Formin-binding protein 1, Formin-binding protein 17, hFBP17, KIAA0554, MGC126804.

    Background: FNBP1 is a 617 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, cytoskeleton, lysosome and the cell cortex, and contains one FCH domain, one REM repeat and one SH3 domain. Expressed at high levels in respiratory, reproductive and urinary systems, as well as in brown adipose tissue and epithelial cells of the gastrointestinal tract, FNBP1 interacts with Rho 7 and links the Actin cytoskeleton with Rho 7 signaling, playing a crucial role in membrane tubulation and cytoskeletal reorganization during endocytosis. Additionally, FNBP1, which exists as four alternatively spliced isoforms, enhances Actin polymerization and promotes membrane invagination and the formation of tubules. Chromosomal aberrations in the FNBP1 gene are associated with acute leukemias, suggesting a role for defective FNBP1 in carcinogenesis.

    ID gène
    23048
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