ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7) anticorps (HRP)

Détails pour le produit réf. ABIN1712102, Fournisseur: Connectez-vous pour afficher
Antigène
  • CG7955
  • Dmel\\CG7955
  • dABCB7
  • GB11034
  • ABCB7
  • fc20c02
  • wu:fc20c02
  • ABC7
  • ASAT
  • Atm1p
  • EST140535
  • AA517758
  • AU019072
  • Abc7
  • CG7955 gene product from transcript CG7955-RA
  • ATP-binding cassette subfamily B, member 7
  • ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • ABCB7-like
  • ATP-binding cassette, subfamily B (MDR/TAP), member 7
  • ABCB7
  • abcb7
  • LOC100367778
  • Abcb7
Reactivité
Humain, Souris, Rat (Rattus)
68
25
24
2
1
1
1
1
1
1
1
1
1
1
Hôte
Lapin
70
Clonalité
Polyclonal
Conjugué
HRP
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
39
31
30
15
13
3
3
2
2
Options
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Immunogène KLH conjugated synthetic peptide derived from human ABCB7
Isotype IgG
Purification Purified by Protein A.
Autre désignation Abcb7 (ABCB7 Antibody Extrait)
Sujet

The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1â€"4 that are known to be present in the human peroxisome membrane (1). All four proteins are ABC half-transporters, which dimerize to form an active transporter (1). A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage (2,3). ABCD2 in mouse, is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD (4). The peroxisomal membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3 (5). ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors (5). ABCD4 localizes to peroxisomes (1). The genes which encode ABCD1â€"4 map to human chromosome Xq28, 12q11-q12, 1p22-p21 and 14q24.3, respectively (3,6â€"8). ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol and maps to human chromosome Xq13.1-q13.3 (9).

Subcellular location: Cytoplasm

Synonyms: ABC transporter 7 protein, ABC7, Abcb7, ABCB7_HUMAN, ASAT, Atm1p, ATP binding cassette 7, ATP binding cassette sub family B MDR/TAP member 7, ATP binding cassette sub family B member 7, ATP binding cassette sub family B member 7 mitochondrial, ATP binding cassette transporter 7, ATP-binding cassette sub-family B member 7, ATP-binding cassette transporter 7, EST140535, MDR7, mitochondrial, Multidrug resistance protein 7, P-glycoprotein 7, PGP7.

ID gène 22
Pathways Transition Metal Ion Homeostasis
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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